A CROSS SECTIONAL STUDY ON THE RATIO OF MULTI DRUG RESISTANCE (MDR) AND EXTENSIVELY DRUG RESISTANT (XDR) BACTERIA IN TRACHEAL ASPIRATES (TA)

Objective: The Multi Drug Resistance (MDR) and Extensively Drug Resistant (XDR) bacteria are usual troubles in the universe mostly in ICUs. We aimed in this study to evaluate antibiotic vulnerability form and rate of bacteria detached to Tracheal Aspirates (TA) of patients in ICU and categorize these in any of the two groups. Study design: A reflective type of cross-sectional study. Place and duration:  This analysis was conducted in the ICU of Holy Family Hospital, Rawalpindi with duration of 01 years from December, 2017 to November, 2018. Methodology: It was a reflective type of study of laboratory records of TA attained from the ICU patients presented for compassion. The Tracheal Aspirates (TA) cases with positive compassion were examined through SPSS 21 by One-way ANOVA procedure for every antibiotic for the treatment of various types of bacteria.The tests were gotten in the sterilize general packages were sophisticated for Blood and Mac Conkey Agar and heated up in the late-night at a temperature of 37 degree centigrade aerobically. The separated bacteria were Gram stained and more treatment was consequently processed. Gram-positive cocci were separated in Streptococci or Staphylococci because of Catalase examination facts. On wise the Staphylococci were classified into Staphylococci epidermis and Staphylococci aureus because of DNA and coagulase analyzations and compassion into Novobiocin disc which is 5.0 µg. Results: Cases with positive and non-productive growth cases from the total of 98 cases were 79 and 19 respectively while 5 cases out of 79 produced two categories of bacteria. From 84 cases which existed for study out of which cases with Gram negative rods and Gram-positive cocci were 61 and 8 respectively. 15 were having fungal growth. The quarantines were categorized into Multi Drug Resistance (MDR), Extensively Drug Resistant (XDR)and having common compassion form. Conclusions: Maximum quarantines were associated with XDR and Minimum with MDR while some with common compassion form with the percentage of 56.5 %, 37.6% and 5.8% respectively. This condition is frightening for the avoidance of illness and treatment of patients in hospitals.

Key Words: Pseudomonas aeruginosa, Drug resistance, Intensive care units, Acinetobacter baumannii, Antibiotic, MDR, XDR, Tracheal Aspirates (TA).