Accelerometer-assessed physical activity and incident diabetes in a population covering the adult life span: The Hispanic Community Health Study/Study of Latinos

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  • Chen, G.-C.
    • Other Affiliation: Albert Einstein College of Medicine
  • Qi, Q.
    • Other Affiliation: Albert Einstein College of Medicine
  • Hua, S.
    • Other Affiliation: Albert Einstein College of Medicine
  • Moon, J.-Y.
    • Other Affiliation: Albert Einstein College of Medicine
  • Spartano, N.L.
    • Other Affiliation: Boston University
  • Vasan, R.S.
    • Other Affiliation: Boston University
  • Sotres-Alvarez, D.
    • Affiliation: Gillings School of Global Public Health, Department of Biostatistics
  • Castaneda, S.F.
    • Other Affiliation: San Diego State University
  • Evenson, K.R.
    • Affiliation: Gillings School of Global Public Health, Department of Epidemiology
  • Perreira, K.M.
    • Affiliation: School of Medicine, Department of Social Medicine
  • Gallo, L.C.
    • Other Affiliation: San Diego State University
  • Pirzada, A.
    • Other Affiliation: University of Illinois, Chicago
  • Diaz, K.M.
    • Other Affiliation: Columbia University Medical Center
  • Daviglus, M.L.
    • Other Affiliation: University of Illinois, Chicago
  • Gellman, M.D.
    • Other Affiliation: University of Miami
  • Kaplan, R.C.
    • Other Affiliation: Fred Hutchinson Cancer Research Center
  • Xue, X.
    • Other Affiliation: Albert Einstein College of Medicine
  • Mossavar-Rahmani, Y.
    • Other Affiliation: Albert Einstein College of Medicine
Abstract
  • Background: The association between accelerometer-assessed physical activity and risk of diabetes remains unclear, especially among US Hispanic/Latino adults who have lower levels of physical activity and a higher diabetes burden compared with other racial/ethnical populations in the country. Objectives: To examine the association between accelerometer-assessed physical activity and incident diabetes in a US Hispanic/Latino population. Methods: We included 7280 participants of the Hispanic Community Health Study/Study of Latinos who aged 18-74 y and free of diabetes at baseline. Data on moderate-to-vigorous physical activity (MVPA) were collected using a 7-d accelerometer measurement. Incident diabetes was assessed after a mean ± SD of 6.0 ± 0.8 y using standard procedures including blood tests. RRs and 95% CIs of diabetes associated with MVPA were estimated using survey Poisson regressions. The associations of MVPA with 6-y changes in adiposity measures were also examined. Results: A total of 871 incident cases of diabetes were identified. MVPA was inversely and nonlinearly associated with risk of diabetes (P-nonlinearity = 0.006), with benefits accruing rapidly at the lower end of MVPA range (<30 min/d) and leveling off thereafter. The association differed by population age (P-interaction = 0.006). Higher MVPA was associated with lower risk of diabetes among individuals older than 50 y (RRQ4 versus Q1 = 0.50; 95% CI: 0.35, 0.73; P-trend < 0.001) but not among younger individuals (RRQ4 versus Q1 = 0.98; 95% CI: 0.66, 1.47; P-trend = 0.92). An inverse association between MVPA and 6-y gain in waist circumference was also limited to the older group (P-interaction with age < 0.001). Conclusions: Among US Hispanic/Latino adults, baseline accelerometer-derived MVPA was inversely associated with incident diabetes only among individuals aged 50 y and older. Further studies are needed to confirm our findings and to clarify potential mechanisms underlying the possible age differences in the MVPA-diabetes association. This study was registered at clinicaltrials.gov as NCT02060344.
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  • Article
Rights statement
  • In Copyright
Journal title
  • American Journal of Clinical Nutrition
Journal volume
  • 112
Journal issue
  • 5
Page start
  • 1318
Page end
  • 1327
Language
  • English
ISSN
  • 0002-9165
Publisher
  • Oxford University Press

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