Samankaltainen aineisto
Näytetään aineistoja, joilla on samankaltainen nimeke tai asiasanat.
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PROX1 transcription factor controls rhabdomyosarcoma growth, stemness, myogenic properties and therapeutic targets
Gizaw, Nebeyu Yosef; Kallio, Pauliina; Punger, Tatjana; Gucciardo, Erika; Haglund, Caj; Böhling, Tom; Lehti, Kaisa; Sampo, Mika; Alitalo, Kari; Kivelä, Riikka (National Academy of Sciences, 2022)Rhabdomyosarcoma (RMS) is an aggressive pediatric soft-tissue cancer with features of skeletal muscle. Because of poor survival of RMS patients and severe long-term side effects of RMS therapies, alternative RMS therapies ... -
Physical activity as a protective factor for dementia and Alzheimer’s disease : systematic review, meta-analysis and quality assessment of cohort and case-control studies
Iso-Markku, Paula; Kujala, Urho M; Knittle, Keegan; Polet, Juho; Vuoksimaa, Eero; Waller, Katja (BMJ Publishing Group, 2022)OBJECTIVE - Physical activity (PA) is associated with a decreased incidence of dementia, but much of the evidence comes from short follow-ups prone to reverse causation. This meta-analysis investigates the effect of study ... -
The underestimated role of winter microclimate for Arctic tundra vegetation
Niittynen, Pekka; Aalto, Juha; Heikkinen, Risto; Luoto, Miska (Open Science Centre, University of Jyväskylä, 2018)Assessing the impacts of climate change on biodiversity and developing climate-wise conservation planning requires in-depth understanding of the key drivers of species distributions and assemblages. This is particularly ... -
Bacterial and fungal communities in sub-Arctic tundra heaths are shaped by contrasting snow accumulation and nutrient availability
Männistö, Minna K.; Ahonen, Saija H. K.; Ganzert, Lars; Tiirola, Marja; Stark, Sari; Häggblom, Max M. (Oxford University Press (OUP), 2024)Climate change is affecting winter snow conditions significantly in northern ecosystems but the effects of the changing conditions for soil microbial communities are not well-understood. We utilized naturally occurring ... -
Vascular endothelial growth factor-A and platelet-derived growth factor-B combination gene therapy prolongs angiogenic effects via recruitment of interstitial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogenic vessels
Korpisalo, P; Karvinen, H; Rissanen, T T; Kilpijoki, J; Marjomäki, Varpu; Baluk, P; McDonald, D M; Cao, Y; Eriksson, U; Alitalo, K; Ylä-Herttuala, S (2008)Vessel stabilization and the inhibition of side effects such as tissue edema are essential in angiogenic gene therapy. Thus, combination gene transfers stimulating both endothelial cell and pericyte proliferation have ...
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