Open Access, Peer-reviewed
pISSN 2384-1079
eISSN 2384-1087
    Korean J Pediatr Infect Dis. 2011 Dec;18(2):173-181. Korean.
    Published online Dec 31, 2011.
    https://doi.org/10.14776/kjpid.2011.18.2.173
    Copyright © 2011 The Korean Society of Pediatric Infectious Diseases
    Original Article

    Clinical and Laboratory Finding of the 2009 Pandemic influenza A (H1N1) in Children

    Yu Rak Sohn, M.D., Su Hyun Park, M.D. and Won Duck Kim, M.D.
      • Department of Pediatrics, Fatima Hospital, Daegu, Korea.
    • Corresponding author (Email: neogubugi@yahoo.co.kr )
    Received July 01, 2011; Revised October 01, 2011; Accepted October 03, 2011.

    Abstract

    Purpose

    2009 Pandemic influenza A (H1N1) virus was identified in March 2009 and subsequently caused worldwide outbreaks. We described the clinical and epidemiological characteristics of H1N1 influenza infection.

    Methods

    We used retrospective medical chart reviews to collect data on the visiting patients from a single institute. H1N1 infection was confirmed in specimens with the use of a RT-PCR (real time reverse transcriptase polymerase chain reaction assay).

    Results

    6,836 patients had H1N1 RT-PCR test, and 2,781 were confirmed with H1N1 virus infection. 158 patients (5.7%) had hospital treatment and inpatients were significantly younger (5.4±3.3 years) than outpatients (7.5±3.9 years) among H1N1 virus confirmed patients. Oxygen, steroid, immunoglobulin, ventilator treatment was provided in a substantial proportion among pneumonia patients accompanying wheezy respiration. In addition more intensive care was needed in patients accompanying segmental, lobar, interstitial, mixed pneumonia and lung effusion (27.2%) than patients with bronchopneumonia (7.3%) among H1N1 virus infection confirmed patients. Seventy-one infants had oseltamivir treatment out of 83 infants under 1 year, and no significant side effects and complications were identified.

    Conclusion

    In 2009 pandemic influenza A (H1N1), hospital treatment was needed in younger patients. Early intensive care was needed in pneumonia patients accompanying wheezy respiration, and patients accompanying segmental, lobar, interstitial, mixed pneumonia and lung effusion.

    Keywords
    H1N1; Pneumonia; Asthma; Oseltamivir

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    MeSH Terms
    Asthma
    Bronchopneumonia
    Child
    Critical Care
    Disease Outbreaks
    Humans
    Immunoglobulins
    Infant
    Influenza A Virus, H1N1 Subtype
    Influenza, Human
    Inpatients
    Lung
    Oseltamivir
    Outpatients
    Oxygen
    Pandemics
    Pneumonia
    Respiration
    Retrospective Studies
    Reverse Transcriptase Polymerase Chain Reaction
    Ventilators, Mechanical
    Viruses
    Metrics
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