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E. Samuli Lepojärvi, Heikki V. Huikuri, Olli-Pekka Piira, Antti M. Kiviniemi, Johanna A. Miettinen, Tuomas Kenttä, Olavi Ukkola, Juha S. Perkiömäki, Mikko P. Tulppo, M. Juhani Junttila
Biomarkers as predictors of sudden cardiac death in coronary artery disease patients with preserved left ventricular function (ARTEMIS study)
www.plosone.org
www.plosone.org
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(.)Tj
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[()12()]TJ
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(guidelines.)Tj
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(ventricular)Tj
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[()108()]TJ
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(mass)Tj
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1.7915 0 Td
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0.7994 0 Td
(0.8)Tj
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1.4003 0 Td
[()]TJ
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0.788 0 Td
([1.04)Tj
2.211 0 Td
({\(LVIDd)Tj
3.7361 0 Td
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0.7993 0 Td
(PWTd)Tj
2.8857 0 Td
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0.7993 0 Td
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Q
q
1 j
1 J
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7.4999 0 0 6.6659 502.8661 464.8251 cm
BT
/F9 1 Tf
1 TL
-0.0053 Tc
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(3)Tj
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Q
q
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(35%)Tj
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3.8438 0 Td
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(cardiologists)Tj
5.2554 0 Td
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(the)Tj
1.4683 0 Td
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(calculator)Tj
4.1329 0 Td
(version)Tj
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(2.11)Tj
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(on)Tj
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(the)Tj
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1.474 0 Td
[()28()63()23()]TJ
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-31.5948 -1.3039 Td
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2.4208 0 Td
(Web)Tj
2.1146 0 Td
(site)Tj
1.5704 0 Td
(\()Tj
0.83 0.64 0.02 0 k
(www.syntaxscore.com)Tj
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1.7858 0 Td
(primary)Tj
3.4526 0 Td
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(the)Tj
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1.4683 0 Td
[()47()]TJ
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4.2576 0 Td
(study)Tj
2.3925 0 Td
(is)Tj
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0.8447 0 Td
[()]TJ
/F9 1 Tf
(,)Tj
2.2167 0 Td
(including)Tj
4.0421 0 Td
(aborted)Tj
3.2882 0 Td
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3.1011 0 Td
(arrests.)Tj
3.067 0 Td
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-35.9884 -1.2983 Td
(occurrence)Tj
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(of)Tj
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1.0148 0 Td
[()]TJ
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1.9956 0 Td
(and)Tj
1.7291 0 Td
(aborted)Tj
3.2882 0 Td
(cardiac)Tj
3.1011 0 Td
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(by)Tj
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(an)Tj
1.2019 0 Td
(endpoint)Tj
3.8607 0 Td
(committee)Tj
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[()]TJ
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-34.299 -1.2983 Td
(and)Tj
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1.7291 0 Td
[()]TJ
/F9 1 Tf
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2.2111 0 Td
(death)Tj
2.4264 0 Td
(certificates)Tj
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4.0422 0 Td
(autopsy)Tj
3.3221 0 Td
(reports,)Tj
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(hospital)Tj
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(records,)Tj
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(and)Tj
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(contacts)Tj
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(kin.)Tj
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(probable)Tj
3.7303 0 Td
(or)Tj
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(possible)Tj
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(sudden)Tj
3.1408 0 Td
(deaths)Tj
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(classified)Tj
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1.0148 0 Td
[()3()]TJ
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(including)Tj
4.0422 0 Td
(wit-)Tj
-34.6562 -1.2983 Td
(nessed)Tj
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(sudden)Tj
3.1351 0 Td
(death)Tj
2.4321 0 Td
(within)Tj
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(one)Tj
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(hour)Tj
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(after)Tj
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(the)Tj
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(symptoms,)Tj
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(or)Tj
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(within)Tj
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(24)Tj
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(hours)Tj
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(the)Tj
1.4684 0 Td
(victim)Tj
2.7495 0 Td
(was)Tj
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(last)Tj
1.5591 0 Td
(seen)Tj
1.9785 0 Td
(alive)Tj
2.041 0 Td
(without)Tj
3.3335 0 Td
(any)Tj
1.6554 0 Td
(evidence)Tj
3.7134 0 Td
(of)Tj
1.0148 0 Td
(non-cardiac)Tj
5.0569 0 Td
(cause)Tj
2.3868 0 Td
(of)Tj
1.0148 0 Td
(death)Tj
2.4321 0 Td
(at)Tj
0.9524 0 Td
(autopsy.)Tj
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1.7802 0 Td
(secondary)Tj
4.2746 0 Td
(endpoint)Tj
3.8551 0 Td
(of)Tj
1.0148 0 Td
(the)Tj
1.4683 0 Td
(study)Tj
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(defined)Tj
3.2258 0 Td
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1.0148 0 Td
(all-cause)Tj
3.6624 0 Td
(mortality)Tj
3.9174 0 Td
(\()Tj
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[()35()]TJ
/F9 1 Tf
(\).)Tj
ET
Q
q
1 j
1 J
0 w
11.9999 0 0 11.9999 200.0125 269.0078 cm
BT
/F17 1 Tf
1 TL
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(Statistical)Tj
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(analyses)Tj
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Q
q
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BT
/F9 1 Tf
1 TL
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(are)Tj
1.4456 0 Td
(expressed)Tj
4.0932 0 Td
(as)Tj
1.0148 0 Td
(mean)Tj
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[()8()]TJ
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(median)Tj
3.2428 0 Td
(\(interquartile)Tj
5.5445 0 Td
(range\))Tj
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(the)Tj
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(of)Tj
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4.5695 0 Td
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2.2507 0 Td
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1.3833 0 Td
(independent)Tj
5.278 0 Td
(samples,)Tj
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6.4799 0 Td
(U-test)Tj
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5.8223 0 Td
(distri-)Tj
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1.4683 0 Td
(data\))Tj
2.2564 0 Td
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1.0998 0 Td
(chi-square)Tj
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2.0636 0 Td
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1.0261 0 Td
(compare)Tj
3.7134 0 Td
(the)Tj
1.4683 0 Td
(survivors)Tj
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(the)Tj
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(groups)Tj
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[()]TJ
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(and)Tj
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1.7291 0 Td
[()35()]TJ
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(.)Tj
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(operating)Tj
4.0536 0 Td
(characteristic)Tj
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(\()Tj
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[()8()-19()]TJ
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(the)Tj
1.4683 0 Td
(optimal)Tj
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(the)Tj
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[()]TJ
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1.9899 0 Td
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(the)Tj
1.474 0 Td
(value)Tj
2.3017 0 Td
(that)Tj
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(pro-)Tj
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4.371 0 Td
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(50%)Tj
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1.0148 0 Td
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3.3675 0 Td
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3.3165 0 Td
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1.7802 0 Td
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4.49 0 Td
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1.0148 0 Td
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4.7792 0 Td
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-34.6051 -1.2983 Td
(assessed)Tj
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4.1839 0 Td
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1.0204 0 Td
(the)Tj
1.4627 0 Td
(recommendations)Tj
7.4948 0 Td
(by)Tj
1.1735 0 Td
(Hlatky)Tj
2.9083 0 Td
(et)Tj
0.9355 0 Td
(al.)Tj
1.1225 0 Td
([)Tj
0.83 0.64 0.02 0 k
(15)Tj
0 g
(].)Tj
2.0692 0 Td
(These)Tj
2.5626 0 Td
(recommendations)Tj
7.4947 0 Td
(sug-)Tj
-35.892 -1.2983 Td
(gest)Tj
1.7688 0 Td
(that)Tj
1.7744 0 Td
(when)Tj
2.4038 0 Td
(a)Tj
0.6576 0 Td
(new)Tj
1.8766 0 Td
(risk)Tj
1.7121 0 Td
(marker)Tj
3.1407 0 Td
(is)Tj
0.8448 0 Td
(introduced)Tj
4.6431 0 Td
(in)Tj
1.0375 0 Td
(a)Tj
0.6519 0 Td
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