Thromb Haemost 2012; 107(05): 827-837
DOI: 10.1160/TH11-09-0611
Review Article
Schattauer GmbH

Infections and inflammatory diseases as risk factors for venous thrombosis

A systematic review
Y. I. G. Vladimir Tichelaar
1   Department of Hematology, Division of Hemostasis and Thrombosis, University Medical Center Groningen, Groningen, the Netherlands
,
Hanneke J. C. Kluin-Nelemans
1   Department of Hematology, Division of Hemostasis and Thrombosis, University Medical Center Groningen, Groningen, the Netherlands
,
Karina Meijer
1   Department of Hematology, Division of Hemostasis and Thrombosis, University Medical Center Groningen, Groningen, the Netherlands
› Author Affiliations
Further Information

Publication History

Received: 06 September 2011

Accepted after major revision: 24 January 2012

Publication Date:
25 November 2017 (online)

Summary

Inflammation and venous thrombosis are intertwined. Only in the recent 15 years clinical epidemiological studies have focussed on inflammatory or infectious diseases as risk factors for venous thrombosis. Although a few reviews and many case reports or studies on these topic has been written, a review reporting relative or absolute risks for venous thrombosis has not been published yet. We performed a systematic review using Medline, Pubmed and Embase and found 31 eligible articles. Inflammatory bowel disease, ANCA-associated vasculitis, infections in general and more specifically, human immunodeficiency virus, pneumonia and urinary tract infections are associated with an increased risk of venous thrombosis.

 
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