Flexible optitrode for localized light delivery and electrical recording

Szu-Te Lin; Mufaddal Gheewala; John A. Dani; John C. Wolfe; Wei-Chuan Shih

doi:10.1117/12.2005707

8 March 2013 Flexible optitrode for localized light delivery and electrical recording

Szu-Te Lin, Mufaddal Gheewala, John A. Dani, John C. Wolfe, Wei-Chuan Shih

Proceedings Volume 8565, Photonic Therapeutics and Diagnostics IX; 85655Y (2013) https://doi.org/10.1117/12.2005707
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

We present two innovative design concepts of integrated flexible neural probe for deep brain optical stimulation and electrical recording, termed as “optitrode”. In the first one, a hybrid annular light pipe is built around a tetrode by V-groove guided capillary assembly (VGCA), by which a single or multiple microwires can be packaged inside the light pipe with high precision. In the second design, thin-film microelectrodes and wires are patterned on an optical fiber by proximity ion beam lithography. These designs address a major limitation on the length-to-diameter ratio, achieving > 500 (>5 cm long, <100 μm diameter). The highly flexible nature of optitrode could be critical for minimally-invasive implantation as well as long-term operation.

Citation Download Citation

Szu-Te Lin, Mufaddal Gheewala, John A. Dani, John C. Wolfe, and Wei-Chuan Shih "Flexible optitrode for localized light delivery and electrical recording", Proc. SPIE 8565, Photonic Therapeutics and Diagnostics IX, 85655Y (8 March 2013); https://doi.org/10.1117/12.2005707

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KEYWORDS

Optical fibers

Brain

Optogenetics

Capillaries

Integrated optics

Silicon

Waveguides

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