Abstract
IRRADIATION with high-energy heavy particles is suitable for the destruction of small selected regions in the central nervous system. Tobias et al.1 irradiated the hypophysis of animals and man with 190-MeV. deuterons and 340-MeV. protons. Anderson et al.2 made lesions in the hypothalamus of the rat using 190-MeV. deuterons. Malis et al.3, making use of the thin ionization peak at the end of the beam, produced lesions at a depth of 0.8 mm. in the cerebral cortex of the cat with 10-MeV. protons. The continuation of animal experiments and the possible application of heavy-particle beams to stereotaxic radiosurgery in man4 5 make it essential to know their effects on the central nervous system in detail.
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References
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Andersson, A., Garcia, J., Henry, J., Riggs, C., Roberts, J. E., Thorell, B., and Tobias, C. A., Radiation Res., 7, 299 (1957).
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Leksell, L., “Handb. d. Neurochirurgie”, 6 (Springer, Berlin, 1957).
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LARSSON, B., LEKSELL, L., REXED, B. et al. The High-Energy Proton Beam as a Neurosurgical Tool. Nature 182, 1222–1223 (1958). https://doi.org/10.1038/1821222a0
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DOI: https://doi.org/10.1038/1821222a0
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