Elsevier

Tetrahedron Letters

Volume 49, Issue 52, 22 December 2008, Pages 7413-7415
Tetrahedron Letters

C–C bond formation from alcohols and malonate half esters using borrowing hydrogen methodology

https://doi.org/10.1016/j.tetlet.2008.10.059Get rights and content

Abstract

Alcohols have been used as alkylating agents in a decarboxylative reaction with malonate half esters via a borrowing hydrogen pathway catalysed by readily available Ru(PPh3)3Cl2.

Graphical abstract

Alcohols have been used as alkylation agents in decarboxylative reactions with half malonates via a borrowing hydrogen pathway catalysed by readily available Ru(PPh3)3Cl2.

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Acknowledgement

We thank the EPSRC for funding a studentship through the Doctoral Training Account (to S.J.P.).

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