Dental implantAerosol Deposition of Hydroxyapatite and 4-Hexylresorcinol Coatings on Titanium Alloys for Dental Implants
Section snippets
Aerosol Deposition Of HA And 4-hr Coatings On Titanium Alloys
The coating method is described in detail elsewhere.25 In brief, titanium specimens (grade IV; Dynamet, Burlington, MA), which were machined into discs with dimensions of 5 mm (diameter) × 0.4 mm (thickness), were used as the substrate. These discs were cleaned ultrasonically in acetone, ethanol, and deionized water. The raw HA powder (Alfar Aesar, Ward Hill, MA) used in this study was subjected to predeposition treatment consisting of heating to 1,050°C for 2 hours and ball milling for 24
Surface Analysis Of 4-HR–coated HA Implant By XRD And FT-IR And Better Cell Attachment
The XRD pattern for HA-coated titanium was well matched to the characteristic hexagonal phase of the stoichiometric HA (ICDD No. 086-0740) (Fig 1A). Relatively strong peak intensity from the titanium compared with that of HA was also observed. When the film was further coated with 4-HR, the diffraction pattern of the HA was still conserved.
The measured infrared absorption spectrum of the HA showed characteristic vibrational modes; 2 vibrational absorptions at 1,090 and 1,024 cm–1 can be
Discussion
Microorganisms can adhere to the HA-coated surface easily as a biofilm and can induce inflammation around the implant fixture.31 4-HR is a well-known ingredient for oral antiseptics.23 HA particles were mixed with 4-HR and coated on a titanium surface. In this study the HA + 4-HR combination coating had a clear advantage compared with the HA coating alone. First, the HA + 4-HR coating had better cellular attachment than the HA coating. Second, the HA + 4-HR coating had higher osteocalcin
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Calcium orthophosphates as a dental regenerative material
2019, Advanced Dental BiomaterialsTopical delivery of 4-hexylresorcinol promotes wound healing via tumor necrosis factor-α suppression
2016, BurnsCitation Excerpt :These effects of 4HR make it an effective anti-cancer agent; in fact, 4HR has been shown to have synergistic effects with cisplatin [11]. Because 4HR has anti-septic activity and inhibits the NF-κB pathway inhibition, dental implants coated with 4HR have been shown to promote better bone formation when contaminated [13]. When 4HR is used with allogenic graft material such as silk, 4HR can inhibits giant cell formation via a diacylglycerol kinase-mediated pathway [14].
Calcium orthophosphate deposits: Preparation, properties and biomedical applications
2015, Materials Science and Engineering CCitation Excerpt :In addition, the HA deposits on Mg with the PCL interlayer were found to have better stability during deformation if compared to those on Mg without the interlayer [572]. Due to the ambient processing conditions, various types of CaPO4-based biocomposites might be deposited by AD [575–578]. For example, to deposit HA/chitosan biocomposites on AZ31 Mg alloy substrates, researchers employed a slit-type nozzle with a 10 × 0.5 mm2 rectangular opening and air as a carrier gas with a flow rate of 30 L/min.
Hydroxyapatite and silk combination-coated dental implants result in superior bone formation in the peri-implant area compared with hydroxyapatite and collagen combination-coated implants
2014, Journal of Oral and Maxillofacial SurgeryCitation Excerpt :Implants from the animals were fixed in 10% formalin and subjected to histomorphometric evaluation. The specimen preparation procedure was identical to that described in previous studies.13,21 The specimens were stained in a Villanueva bone staining solution for 7 days.
Hydroxyapatite and collagen combination-coated dental implants display better bone formation in the peri-implant area than the same combination plus bone morphogenetic protein-2-coated implants, hydroxyapatite only coated implants, and uncoated implants
2014, Journal of Oral and Maxillofacial SurgeryCitation Excerpt :The implants from the animals were fixed in 10% formalin and subjected to histomorphometric evaluation. The procedure for the specimen preparation is the same as described in a previous study.18 Briefly, after the dehydration procedure, the specimen was embedded in methylmethacrylate resin.
The current applications of nano and biomaterials in drug delivery of dental implant
2024, BMC Oral Health
This study was supported by grants from the Korea Science and Engineering Foundation and Ministry of Education, Science and Technology (The Regional Core Research Program); grant R32-10064 from the WCU Project of the Ministry of Education, Science and Technology and the Korea Science and Engineering Foundation; and Brain Korea 21 Project in 2010. This research was partly supported by a grant from the Fundamental R&D Program for Core Technology of Materials funded by the Ministry of Knowledge Economy, Republic of Korea. This study was also supported by a grant from the BioGreen21 Program (No. PJ007170201006) and the Rural Development Administration, Suwon, Republic of Korea.