Journal of the Academy of Nutrition and Dietetics
ResearchResearch and Professional BriefsEffect of Ground Cinnamon on Postprandial Blood Glucose Concentration in Normal-Weight and Obese Adults
Section snippets
Methods
The protocol was reviewed and approved by Ball State University's Institutional Review Board, and all subjects provided written informed consent prior to study participation. Subjects were recruited at Ball State University from February through April 2010. Normal-weight (body mass index [BMI]=18.5 to 24.9) and obese (BMI ≥30.0) individuals age 18 to 30 years were eligible for the study. Exclusion criteria included a known allergy to wheat, cinnamon, and/or sucralose; pregnancy; and medical
Subjects
Thirty-seven men and women, age 18 to 30 years, were recruited for the study. A total of seven individuals (five normal-weight and two obese) did not complete the study; one did not report for testing, one left the study for personal reasons, and five did not finish the cereal in the allotted time (three served plain cereal and two served cereal with cinnamon). Subject characteristics are summarized in Table 1. Of the 30 subjects (24 female and 5 male) who completed the study, 28 were white
Conclusions
Findings from the current study provide support for the hypoglycemic effect of cinnamon in healthy individuals during the postprandial period. Critical questions for future research are (a) whether the reduction of blood glucose is maintained with long-term cinnamon supplementation and (b), if so, whether the reduction can delay or prevent the development of type 2 diabetes mellitus and related disease states. As health care in the United States continues to shift from an illness model toward
Acknowledgements
The authors thank the following individuals for their service as research assistants: L. Bollinger, C. Peaks, S. Faith, S. Line, L. Smith, H. Quade, A. Siela, N. Kremer, M. Deroo, and T. Bianski.
A. Magistrelli is a graduate student, Department of Family and Consumer Sciences, Ball State University, Muncie, IN.
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Cited by (38)
Ceylon cinnamon: a versatile ingredient for futuristic diabetes management
2022, Journal of Future FoodsPhytochemical and pharmacological review of Cinnamomum verum J. Presl-a versatile spice used in food and nutrition
2021, Food ChemistryCitation Excerpt :Dugoua et al. (2012) examined the antidiabetic role of C. verum in combination with C. aromaticum on fifty patients of T2D and found no significant improvement in patients. Magistrelli and Chezem (2012) examined the cinnamon effect in thirty adults of normal weight and obesity. They observed that cinnamon has decreased blood sugar concentration and induced more insulin sensitivity during the postprandial period.
Beneficial effects of cinnamon on cardiovascular risk factors and type 2 diabetes
2021, Functional Foods and Nutraceuticals in Metabolic and Non-communicable DiseasesA tale of two cinnamons: A comparative review of the clinical evidence of Cinnamomum verum and C. cassia as diabetes interventions
2020, Journal of Herbal MedicineCitation Excerpt :Among these studies, three trials used C. cassia (Gutierrez et al., 2016; Magistrelli and Chezem, 2012; Wickenberg et al., 2014) (n = 72) and one trial used C. verum (Wickenberg et al., 2012) (n = 10). Three trials were conducted on postprandial glucose levels using an oral glucose tolerance test with cinnamon intake at the test (Gutierrez et al., 2016; Wickenberg et al., 2012; Magistrelli and Chezem, 2012). Intake of C. cassia 5−6 g reduced postprandial glucose levels in obese individuals (Gutierrez et al., 2016; Magistrelli and Chezem, 2012), while C. verum 6 g had no effect in IGT patients (Wickenberg et al., 2012).
Polyphenol-rich spice-based beverages modulated postprandial early glycaemia, appetite and PYY after breakfast challenge in healthy subjects: A randomized, single blind, crossover study
2017, Journal of Functional FoodsCitation Excerpt :In comparison to control, the current study showed that the cinnamon beverage reduced early phase blood glucose by −39% while no changes were observed for either insulin secretion or sensitivity. Our results on glucose lowering effects of cinnamon are in agreement with previous acute studies incorporating different amounts of cinnamon (6 g; 6 g, 5 g; 6 g; respectively) into different type of challenge meals (rice pudding (16 g CHO); 75 g bolus of dextrose; 75 g bolus of dextrose and cereal (50 g CHO) challenge, respectively) (Bernardo et al., 2015; Hlebowicz et al., 2007; Magistrelli & Chezem, 2012; Solomon & Blannin, 2007). Previous study showed that acute cinnamon intake with rice pudding reduced early blood glucose (iAUC 0–45 min) by −55% (Hlebowicz et al., 2007) compared with rice pudding alone.
A. Magistrelli is a graduate student, Department of Family and Consumer Sciences, Ball State University, Muncie, IN.
J. C. Chezem is an associate professor of nutrition, Department of Family and Consumer Sciences, Ball State University, Muncie, IN.
FUNDING/SUPPORT This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.
STATEMENT OF POTENTIAL CONFLICT OF INTEREST No potential conflict of interest was reported by the authors.