Elsevier

The Lancet

Volume 295, Issue 7639, 24 January 1970, Pages 163-164
The Lancet

ADULT CŒLIAC DISEASE IN HYPOSPLENIC PATIENTS

https://doi.org/10.1016/S0140-6736(70)90405-8Get rights and content

Abstract

In a six-month period 25,012 blood-films from 17,140 patients were examined in a routine hæmatology laboratory. 18 cases of hyposplenism were detected. In 16 the cause was surgical splenectomy. In the other 2 cases, previously unsuspected cœliac disease was demonstrated by jejunal biopsy (subtotal villous atrophy) and weight gain on gluten withdrawal. The diagnosis of cœliac disease should be considered in any patient found to have idiopathic hyposplenism.

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