Configurational studies on 2-[∝-(2-ethoxyphenoxy)benzyl] morpholine fce 20124

doi:10.1016/S0040-4020(01)96541-X

Tetrahedron

Volume 41, Issue 7, 1985, Pages 1393-1399

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Abstract

The relative configuration of the two diastereoisomers of (±)2-[∢-(2-ethoxyphenoxy)benzyl] morpholine is determined by a synthesis involving regio and stereo specific reactions. (RS,RS) diastereoisomer FCE 20124 was separated into its (+) and (-) enantiomers both by crystallization of the optically active mandelate salt and by a multi-step synthesis from (+)-(2S,3R)-3-phenylglycidic acid.

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Configurational studies on 2-[∝-(2-ethoxyphenoxy)benzyl] morpholine fce 20124

Abstract

Tetrahedron

Eur. J. Med. Chem.

Bull. Chem. Soc. Japan