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Vaccine therapy in non—small-cell lung cancer

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Abstract

Lung cancer is the leading cause of death from cancer worldwide. First-line therapy is based on stage at diagnosis can include chemotherapy, radiation, and surgery. Despite advances, the prognosis for advanced-stage lung cancer is very poor. Vaccines with the capability to activate the host immune system may have a role in second-line therapy. Advances in the understanding of cellular and molecular immunology are forming the basis for improving vaccine therapy. Most trials to date have demonstrated safety but inconsistent efficacy. Further research is needed to enhance this potential.

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Authors and Affiliations

  1. Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA

    Carol Albright MD, PhD

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  1. Carol Albright MD, PhD
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  2. Jennifer Garst MD
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Correspondence to Carol Albright MD, PhD.

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Albright, C., Garst, J. Vaccine therapy in non—small-cell lung cancer. Curr Oncol Rep 9, 241–246 (2007). https://doi.org/10.1007/s11912-007-0029-9

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