Abstract
Background
There is limited data on chemotherapy for advanced ovarian cancer during pregnancy. Most women received cisplatin-based chemotherapy. There are no published reports on the use of docetaxel for ovarian cancer in pregnancy.
Case
A 32-year-old pregnant lady underwent laparatomy at 18-week gestation for ruptured ovarian cyst. The pregnancy was the result of in vitro fertilization with intracytoplasmic sperm injection. Left salpingo-oophorectomy and omental biopsy were done. A diagnosis of stage IIIC, poorly differentiated papillary serous adenocarcinoma of the ovary was made. She was given four cycles of cisplatinum and docetaxel followed by cesarean hysterectomy, right salpingo-oophorectomy, and cytoreductive surgery. The mother is well and has completed six cycle of chemotherapy.
Conclusion
This is the first report on the use of docetaxel during pregnancy for ovarian cancer.
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Rouzi, A.A., Sahly, N.N., Sahly, N.F. et al. Cisplatinum and docetaxel for ovarian cancer in pregnancy. Arch Gynecol Obstet 280, 823–825 (2009). https://doi.org/10.1007/s00404-009-0992-5
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DOI: https://doi.org/10.1007/s00404-009-0992-5