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The choroid plexus: a comprehensive review of its history, anatomy, function, histology, embryology, and surgical considerations

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An Erratum to this article was published on 22 December 2013

Abstract

Introduction

The role of the choroid plexus in cerebrospinal fluid production has been identified for more than a century. Over the years, more intensive studies of this structure has lead to a better understanding of the functions, including brain immunity, protection, absorption, and many others. Here, we review the macro- and microanatomical structure of the choroid plexus in addition to its function and embryology.

Method

The literature was searched for articles and textbooks for data related to the history, anatomy, physiology, histology, embryology, potential functions, and surgical implications of the choroid plexus. All were gathered and summarized comprehensively.

Conclusion

We summarize the literature regarding the choroid plexus and its surgical implications.

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Authors and Affiliations

  1. Department of Neurological Surgery, University of Alabama at Birmingham, Birmingham, AL, USA

    Martin M. Mortazavi & Christoph J. Griessenauer

  2. Department of Neurological Surgery, The Children’s Hospital of Alabama, Birmingham, AL, USA

    Nimer Adeeb, Aman Deep, Richard Isaiah Tubbs & R. Shane Tubbs

  3. Comprehensive Stroke Center, University of Alabama Hospital, Birmingham, AL, USA

    Reza Bavarsad Shahripour

  4. Department of Anatomical Sciences, St. George’s University, True Blue, Grenada

    Marios Loukas & R. Shane Tubbs

  5. Centre of Anatomy and Human Identification, Dundee University, Dundee, UK

    R. Shane Tubbs

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  1. Martin M. Mortazavi
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Correspondence to R. Shane Tubbs.

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Mortazavi, M.M., Griessenauer, C.J., Adeeb, N. et al. The choroid plexus: a comprehensive review of its history, anatomy, function, histology, embryology, and surgical considerations. Childs Nerv Syst 30, 205–214 (2014). https://doi.org/10.1007/s00381-013-2326-y

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