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Effects of the implantation of Ommaya reservoir in children with tuberculous meningitis hydrocephalus: a preliminary study

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Abstract

Objective

The role of Ommaya reservoir implantation in children with tuberculous meningitis hydrocephalus (TBMH) has been seldomly reported. Therefore, we performed this study to determine the role of the Ommaya reservoir in the treatment of children with TBMH.

Methods

We retrospectively analyzed the effects of Ommaya reservoir implantation in 12 children with TBMH. Intracapsular puncture of the reservoir was performed for draining the cerebrospinal fluid and the TBM was treated by intraventricular injection of isoniazid.

Results

The ideal treatment outcome was observed in nine (75 %) of the 12 children; two (16.7 %) children developed serious disabilities and one of them (8.3 %) eventually died. The treatment method was effective for all six (100 %) children with Palur grade II TBM but showed no effect in three (50 %) children with grade III and IV TBM. The number of leukocytes in the cerebrospinal fluid decreased to 20 × 106/L (75 %) within 2 weeks after implantation of the reservoirs. Finally, the Ommaya reservoirs in eight children were removed but were retained in four children. Four children had to undergo ventriculoperitoneal shunt.

Conclusion

Ommaya reservoir implantation has been shown to be effective in treating children with TBMH. This method may be largely suitable for children with early grade II TBM or partly in children with grade III TBM who have mild or moderate hydrocephalus that can alleviate after short-term treatment. Thus, a good proportion of children who undergo Ommaya reservoir implantation can avoid ventriculoperitoneal shunt surgery.

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Acknowledgments

This study was supported by Foundation of Science and Technology Department of Zhejiang Province of China (No. 2010C33090).

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Authors and Affiliations

  1. Department of Neurosurgery, Yuying Children’s Hospital of Wenzhou Medical Collage, Wenzhou, China, 325027

    Jian Lin, Hui Zhou, Nu Zhang, Bo Yin & Hang-song Sheng

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  1. Jian Lin
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  2. Hui Zhou
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Correspondence to Nu Zhang.

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Lin, J., Zhou, H., Zhang, N. et al. Effects of the implantation of Ommaya reservoir in children with tuberculous meningitis hydrocephalus: a preliminary study. Childs Nerv Syst 28, 1003–1008 (2012). https://doi.org/10.1007/s00381-012-1748-2

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  • DOI: https://doi.org/10.1007/s00381-012-1748-2

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