Abstract
We report on a 4-year-old boy who presented to the ophthalmology department for assessment of convergent strabismus. Ophthalmic examination showed a left morning glory optic disc anomaly and retinal detachment. Plain films obtained for investigation of short stature prior to ophthalmic examination revealed delayed bone age. Ophthalmological findings prompted CT and MRI imaging and angiographic investigations. Midline cranial defects and abnormal carotid circulation were identified. These findings may be associated with morning glory optic disc anomaly, and their association is often under-recognized. It is important that clinicians and radiologists be aware of this spectrum of disorders, as the vascular abnormalities may predispose the patient to transient ischemic attacks and strokes. Growth delay may result from hypopituitarism.
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Suzuki J, Takaku A, Kodama N, et al (1975) An attempt to treat cerebrovascular ’moyamoya’ disease in children. Child’s Brain 1:193–206
Bakri SJ, Siker D, Masaryk T, et al (1999) Ocular malformations, moyamoya disease, and midline cranial defects: a distinct syndrome. Am J Ophthalmol 127:356–357
Goldhammer Y, Smith JL (1975) Optic nerve anomalies in basal encephalocele. Arch Ophthalmol 93:115–118
Hanson MR, Price RL, Rothner AD, et al (1985) Developmental anomalies of the optic disc and carotid circulation—a new association. J Clin Neuro-ophthalmol 5:3–8
Komiyama M, Yasui T, Sakamoto H, et al (2000) Basal meningoencephalocele, anomaly of optic disc and panhypopituitarism in association with moyamoya disease. Pediatr Neurosurg 33:100–104
Krishnan C, Roy A, Traboulsi E (2000) Morning glory disk anomaly, choroidal coloboma, and congenital constrictive malformations of the internal carotid arteries (moyamoya disease). Ophthalmic Genet 21:21–24
Massaro M, Thorarensen O, Liu GT, et al (1998) Morning glory disc anomaly and moyamoya vessels. Arch Ophthalmol 116:253–254
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Quah, B.L., Hamilton, J., Blaser, S. et al. Morning glory disc anomaly, midline cranial defects and abnormal carotid circulation: an association worth looking for. Pediatr Radiol 35, 525–528 (2005). https://doi.org/10.1007/s00247-004-1345-y
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DOI: https://doi.org/10.1007/s00247-004-1345-y