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In situ localization of ACTH receptor-like mRNA in molluscan and human immunocytes

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Abstract

Adrenocorticotropin hormone (ACTH) receptor-like messenger RNA was localized in molluscan hemocytes and human peripheral blood mononuclear cells by in situ hybridization using a digoxigenin-labelled bovine complementary DNA probe. These findings suggest that the ACTH receptor gene has been highly conserved during evolution. Moreover, these data represent further support for a relationship between the immune and neuroendocrine systems in invertebrates, as documented in our previous studies [1].

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Authors and Affiliations

  1. Department of Animal Biology, University of Modena, Via Berengario 14, I-41100 Modena (Italy), Fax +39 59 226769, e-mail: enzott@unimo.it, IT

    E. Ottaviani & A. Franchini

  2. The College of Judea and Samaria, E. Katzir Biotechnology Program, The Research Institute, Ariel 44837 (Israel), IS

    I. Hanukoglu

Authors
  1. E. Ottaviani
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  2. A. Franchini
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  3. I. Hanukoglu
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Additional information

Received 25 September 1997; received after revision 12 November 1997; accepted 12 November 1997

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Ottaviani, E., Franchini, A. & Hanukoglu, I. In situ localization of ACTH receptor-like mRNA in molluscan and human immunocytes. CMLS, Cell. Mol. Life Sci. 54, 139–142 (1998). https://doi.org/10.1007/s000180050133

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  • DOI: https://doi.org/10.1007/s000180050133

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