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Cyclosporin A and C

New metabolites fromTrichoderma polysporum (Link ex Pers.) Rifai

  • Industrial Microbiology
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European journal of applied microbiology and biotechnology Aims and scope Submit manuscript

Summary

Cyclosporin A and C are new antifungal antibiotics fromTrichoderma polysporum (Link ex Pers.) Rifai. The metabolites are produced in submerged culture and are extracted therefrom by organic solvents. Cyclosporin A is a nonpolar cyclic peptide with a molecular weight of 1202.6. The cyclosporins exhibit a narrow spectrum of antifungal activity and in addition have immunosuppressive properties.

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References

  • Arx von,J.A. (1970). The genera of fungi sporulating in pure culture. Lehre: J. Cramer

    Google Scholar 

  • Bartnicki-Garcia,S. (1968). Ann. Rev. Microbiol.22, 87–108

    Google Scholar 

  • Bartnicki-Garcia,S., Lippmann,E. (1972). J. Gen. Microbiol.71, 301–309

    Google Scholar 

  • Bigger,C.H., White,M.H., Braymer,H.D. (1972). J. Gen. Microbiol.71, 159–166

    Google Scholar 

  • Borel,J.F., Feurer,C., Gubler,H.U., Stähelin,H. (1976). Agents and Actions6, 432–440

    Google Scholar 

  • Rifai,M.A. (1969). A revision of the genus Trichoderma. Mycol.Pap.116

  • Rüegger,A., Kuhn,M., Lichti,H., Loosli,H.R., Huguenin,R., Quiquerez,C., von Wartburg,A. (1976). Helv. Chim. Acta59, 1075–1092

    Google Scholar 

  • Petcher,T.J., Weber,H.P. (1976). Helv. Chim. Acta59, 1480–1488

    Google Scholar 

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Authors and Affiliations

  1. Pharmaceutical Division, Chemical Research, Sandoz Ltd., Basle, Switzerland

    M. Dreyfuss, E. Härri, H. Hofmann, H. Kobel, W. Pache & H. Tscherter

Authors
  1. M. Dreyfuss
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  2. E. Härri
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  3. H. Hofmann
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  4. H. Kobel
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  5. W. Pache
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  6. H. Tscherter
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Dreyfuss, M., Härri, E., Hofmann, H. et al. Cyclosporin A and C. European J. Appl Microbiol. 3, 125–133 (1976). https://doi.org/10.1007/BF00928431

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  • DOI: https://doi.org/10.1007/BF00928431

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