Abstract
White blood cell (WBC)99mTc-hexamethylpropyleneamineoxime (HMPAO) scintigraphy was performed in a patient with eosinophilic gastroenteritis. WBC accumulation was detected in the terminal ileum to descending colon, and pathological studies demonstrated eosinophilic infiltration at the same region.99mTc-HMPAO-WBC scintigraphy was proved to be a useful tool for the detection of eosinophilic infiltration in eosinophilic gastroenteritis.
Similar content being viewed by others
References
Kaijser R. Zur Kenntnis der allegischen Affektioner desima Verdauungskanal von Standpunkt desima Chirurgen aus.Arch Klin Chir 1937; 188: 36–64.
Keshavarzian A, Saverymuttu SH, Tai PC, et al. Activated eosinophils in familial eosinophilic gastroenteritis.Gastroenterology 1985; 88: 1041–1049.
Cello JP. Eosinophilic gastroenteritis—a complex disease entity.Am J Med 1979; 67: 1097–1104.
Goldberg HI, O’Kieffe D, Jenis EH, Boyce HW. Diffuse eosinophilic gastroenteritis.Am J Roentgenol Radium ther Nuc Med 1973; 119: 342–351.
Haberkern CM, Christie DL, Haas JE. Eosinophilic gastroenteritis presenting as ileocolitis.Gastroenterology 1978; 74: 896–899.
Klein NC, Hargrove RL, Sleisenger MH, Jeffries GH. Eosinophilic gastroenteritis.Medicine 1970; 49: 299–319.
Moots RJ, Prouse P, Gumpel JM. Near fatal eosinophilic gastroenteritis responding to oral sodium chromoglycate.Gut 1988; 29: 1282–1285.
Lee KJ, Hahm KB, Kim YS, Kim JH, Cho SW, Jie H, et al. The usefulness of99mTc-HMPAO labeled WBC SPECT in eosinophilic gastroenteritis.Clin Nucl Med 1997; 22: 536–541.
Puncher MRB, Blower PJ. Autoradiography and density gradient separation of technetium-99m-Exametazime (HMPAO) labeled leucocytes reveal selectivity for eosinophils.Eur J Nucl Med 1994; 21: 1175–1182.
Colak T, Gungor F, Ozugur S, Bozan H, Yildiz A, Boz A, et al. The value of99mTc-HMPAO labelled white blood cell scintigraphy in acute appendicitis patients with an equivocal clinical presentation.Eur J Nucl Med 2001; 28: 575–580.
Bennink R, Peeters M, D’Haens G, Rutgeerts P, Mortelmans L.99mTc-HMPAO white blood cell scintigraphy in the assessment of the extent and severity of an acute exacerbation of ulcerative colitis.Clin Nucl Med 2001; 26: 99–104.
Malcolm PN, Bearcroft CP, Pratt PG, Rampton DS, Garvie NW. Technetium-99m hexamethylpropyleneamineoxime labeled leucocyte scanning in the diagnosis of Crohn’s disease.Br J Radiol 1994; 67: 964–968.
Japan Isotope Society. Standard nuclear medicine imaging protocol.Radioisotopes 1994; 43: 103–104. (in Japanese).
Ell PJ, Hocknell JMK, Jarritt PH. A99mTc labelled radio tracer for the investigation of cerebral vascular disease.Nucl Med Commun 1985; 6: 437–441.
Peters AM, Danpure HJ, Osman S, Hawker RJ, Henderson BL, Hodgson HJ, et al. Clinical experience with99mTc-hexamethylpropyleneamineoxime for labelling leucocytes and imaging inflammation.Lancet 1986; 25: 946–949.
Roddie ME, Peters AM, Danpure HJ, et al. Inflammation: imaging with Tc-99m HMPAO-labeled leukocytes.Radiology 1988; 166: 767–772.
Saitoh Y, Aburano T, Takashio T, Shuke N, Ayabe T, Nomura M, et al. Clinical Evaluation of99mTc-HMPAO Labeled leukocyte Imaging in Ulcerative Colitis.KAKU IGAKU (Jpn J Nucl Med) 1996; 33: 711–719. (in Japanese)
Quirce R, Carril JM, Gutierrez-Mendiguchia C, Serrano J, Rabasa JM, Bernal JM. Assessment of the diagnostic capacity of planar scintigraphy and SPECT with99mTc-HMPAO-labelled leukocytes in superficial and deep sternal infections after median sternotomy.Nucl Med Commun 2002; 23: 453–459.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Imai, E., Kaminaga, T., Kawasugi, K. et al. The usefulness of99mTc-hexamethylpropyleneamineoxime white blood cell scintigraphy in a patient with eosinophilic gastroenteritis. Ann Nucl Med 17, 601–603 (2003). https://doi.org/10.1007/BF03006675
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF03006675