Summary
A cDNA probe corresponding to mRNA encoding human uroporphyrinogen decarboxylase (URO-D) was used to determine the chromosomal localization of the URO-D gene in the human genome. In agreement with previous studies, we have found that the locus for URO-D is located on chromosome 1 in hybrid cell mapping panels. The use of in sity hybridization allowed us to map the URO-D locus to band 1p34.
References
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Part of this work was presented as an abstract entitled “Localization of the uroporphyrinogen decarboxylase gene to 1p34 band, by in situ hybridization”, by M. G. Mattei, A. Dubart, D. Beaupain, M. Goossens, and J. F. Mattei, for a poster presentation at the 8th International Conference on Human Gene Mapping, Helsinki, August 4–10, 1985
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Dubart, A., Mattei, M.G., Raich, N. et al. Assignment of human uroporphyrinogen decarboxylase (URO-D) to the p34 band of chromosome 1. Hum Genet 73, 277–279 (1986). https://doi.org/10.1007/BF00401245
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DOI: https://doi.org/10.1007/BF00401245