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Electrofluorination of Organic Compounds

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Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 193))

Abstract

The three principal electrochemical methods are described by which fluorine can be directly introduced into organic compounds, namely electrolysis in molten salts or fluoride ion solutions, electrolysis in molten potassium fluoride/hydrogen fluoride melts at porous anodes, and electrolysis in anhydrous hydrogen fluoride at nickel anodes. Using examples from the past decade, it is aimed to demonstrate that electrofluorination in its various forms has proved to be an increasingly versatile tool in the repertoire of the synthetic chemist. Each method is described in terms of its essential characteristics, reaction parameters, synthetic utility, advantages and disadvantages, patent protection, and potential for commercial exploitation. The different mechanisms proposed to explain each process are critically reviewed.

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Drakesmith, F.G. (1997). Electrofluorination of Organic Compounds. In: Chambers, R.D. (eds) Organofluorine Chemistry. Topics in Current Chemistry, vol 193. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-69197-9_5

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  • DOI: https://doi.org/10.1007/3-540-69197-9_5

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