Regular ArticleImmune evasion as a pathogenic mechanism of varicella zoster virus
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2018, Journal of Allergy and Clinical ImmunologyDisseminated Varicella infection in an adult burn victim-A transfused disease?
2009, BurnsCitation Excerpt :There are few reports regarding Varicella infections in burn patients, all regarding children, they cause increased morbidity including scarring and delayed wound healing [3]. Both humeral immunity and cell-mediated immunity are important factors in the severity of VZV infection [5]. Burn and trauma patients suffer from a reduction in their cellular immunocompetence until wounds are closed [6], putting them at increased risk for VZV infection and reactivation.
Expression profiles of genes within a subregion of chicken major histocompatibility complex B in spleen after Marek's disease virus infection
2010, Poultry ScienceCitation Excerpt :As for the MHC-II gene, its expression can also be downregulated by herpesviruses (Hegde et al., 2003). For instance, varicella zoster virus, human cytomegalovirus, mouse cytomegalovirus, and herpes simplex virus 1 suppress interferon (IFN)-induced MHC-II upregulation at the transcriptional level by disrupting the classic IFN pathway (Heise et al., 1998; Le Roy et al., 1999; Miller and Sedmak, 1999; Abendroth et al., 2000; Abendroth and Arvin, 2001; Yokota et al., 2001). Regarding MDV, however, its effects on MHC-II gene expression seem to be variable.
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Corresponding author. 300 Pasteur Dr, Rm G312, Stanford University School of Medicine, Stanford, CA, 94305-5208, USA. Email: [email protected]