AI-assisted decision-making for severe AS

ORIGINAL RESEARCH

May 8
AI-assisted decision-making for severe AS
Adil Salihu et al.
This study evaluated the ability of ChatGPT-4, a large language model, to assist in the decision-making process of Multidisciplinary Heart Teams for the management of severe aortic stenosis, finding a 77% agreement rate with the Heart Team's decisions.

RESEARCH CORRESPONDENCE

May 8
Transcaval VA-ECMO
Gennaro Giustino, Pedro A. Villablanca et al.
This study reports the outcomes of 22 patients with refractory cardiogenic shock who underwent transcaval venoarterial extracorporeal membrane oxygenation, with a 54.6% in-hospital mortality rate and a high incidence of vascular and bleeding complications.
Transcaval VA-ECMO

EDITORIAL

May 8
Can artificial intelligence help Heart Teams make decisions?
Valentin Koch
A study examines the use of ChatGPT in augmenting the decision-making processes of Heart Teams in the treatment of severe aortic stenosis, suggesting a high degree of alignment between the language model and the multidisciplinary teams.
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EDITORIAL

Apr 23
The miracle of left ventricular recovery after transcatheter aortic valve implantation
Harold L. Dauerman, Rony Lahoud et al.
This study examined the outcomes of 914 patients with severely reduced left ventricular ejection fraction (≤30%) who underwent TAVI, finding that prior myocardial infarction, reduced kidney function, and low-flow, low-gradient aortic stenosis were associated with higher mortality.
free

EDITORIAL

Apr 23
Timing of revascularisation in acute coronary syndromes with multivessel disease – two sides of the same coin
Barbara E. Stähli, Julia Stehli et al.
This substudy of the BIOVASC trial suggests that immediate multivessel PCI is an effective and safe strategy for ACS patients with multivessel coronary artery disease, including complex three-vessel disease.
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Apr 27
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ORIGINAL RESEARCH

Apr 23
Left ventricle recovery following TAVI
Guy Witberg, Ran Kornowski et al.
This study assessed the likelihood of left ventricular recovery following transcatheter aortic valve implantation in patients with severe left ventricular dysfunction and severe aortic stenosis, and found that recovery was a major determinant of midterm mortality.
Left ventricle recovery following TAVI
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FAITAVI trial design

TRIAL DESIGN

Apr 23
FAITAVI trial design
Flavio Ribichini, Giuseppe Tarantini et al.
FAITAVI is a randomized trial comparing angiography-guided versus physiology-guided coronary revascularization in patients with severe aortic valve stenosis and coronary artery disease undergoing TAVI.
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ORIGINAL RESEARCH

Apr 17
Immediate complete revascularisation in ACS and MVD
In patients with acute coronary syndrome and multivessel disease, immediate complete revascularization was non-inferior to staged revascularization in terms of the primary endpoint at 1 year, and was associated with a lower rate of myocardial infarction in those with three-vessel disease.
Immediate complete revascularisation in ACS and MVD

ORIGINAL RESEARCH

Apr 1
Crushed prasugrel loading dose in STEMI patients
Jeroen M. Wilschut, Roberto Diletti, et al.
In STEMI patients with a prehospital large myocardial area at risk, administration of crushed prasugrel loading dose was associated with higher post-procedural TIMI 3 flow rates compared to integral prasugrel.
Crushed prasugrel loading dose in STEMI patients

ORIGINAL RESEARCH

Mar 29
Biological differences in paclitaxel- and sirolimus-coated balloons
Kazuki Aihara, Gaku Nakazawa, et al.
This preclinical study compared the drug effects and safety of low-dose paclitaxel, regular-dose paclitaxel and sirolimus-coated drug-coated balloons when inflated in rabbit iliac arteries. Paclitaxel-coated balloons showed higher efficacy and lower distal embolization risk than the sirolimus-coated balloon.
Biological differences in paclitaxel- and sirolimus-coated balloons

Mar 18
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EDITORIAL

Mar 18
Comparative preclinical assessment of DCBs
Michael Joner; Léa Wild
A study compared three drug-coated balloon formulations in a porcine model, assessing drug transfer and tissue distribution as surrogates for clinical efficacy. Both paclitaxel formulations showed greater smooth muscle cell loss than the sirolimus formulation, but limitations were present.
Comparative preclinical assessment of DCBs
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DEBATE

Mar 18
Ischaemic and viability testing for guiding PCI are overrated: pros and cons
Margaret B. McEntegart; Victoria Delgado et al.
Two large randomized trials found no benefit of an invasive strategy guided by ischaemia and viability testing over medical therapy alone for stable CAD patients, challenging the clinical usefulness of such testing.
Ischaemic and viability testing for guiding PCI are overrated: pros and cons
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The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

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