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II. Characterizations of Alginate-Chitosan Hydrogel for Wound Dressing Application
Abstract:
The aim of this study is to evaluate the characterizations of alginate-chitosan hydrogel for wound dressing application. The influence of alginate concentrations (1%, 2%, 3% and 4% (w/v)) was investigated. An increase in alginate concentration leads to a decrease in swelling capacity but an increase in holding capacity. All the hydrogels exhibited above 80% water holding abilities. The hydrogel leach outs were nontoxic to the cells, as confirmed by MTT assay. Taken together these results point out that alginate-chitosan polyelectrolyte hydrogel can be considered for wound dressing applications.
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Periodical:
Pages:
3124-3128
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Online since:
March 2012
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