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Influence of Chondroitin Sulfate A on Zeta Potential, Aggregation and Sedimentation of Nano COM and Nano COD Crystallites
Abstract:
The influence of urinary macromolecule chondroitin sulfate A (C4S) on Zeta potential, aggregation and sedimentation of calcium oxalate monohydrate (COM) and calcium oxalate dihydrate (COD) nanocrystallites with a diameter of about 50 nm were investigated using nanoparticle size Zeta potential analyzer and transmission electron microscope. C4S could increase the absolute value of Zeta potential on surface of nanoCOM and nanoCOD crystallites by adsorbing on crystal surface, it led an increase of the electrostatic repulsion force between the crystallites, so the aggregation and sedimentation of these crystallites were inhibited, and the stability of the suspension of nanoCOM and nanoCOD was improved. In conclusion, C4S could inhibit the formation of CaOxa stones。
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38-42
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May 2014
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