Welcome to the InfoSci Platform
Mitochondrial Dysfunction in Aging and Neurodegeneration

Mitochondrial Dysfunction in Aging and Neurodegeneration

Vaibhav Walia, Munish Garg
Copyright: © 2019 |Pages: 26
ISBN13: 9781522552826|ISBN10: 1522552820|EISBN13: 9781522552833
DOI: 10.4018/978-1-5225-5282-6.ch004
Cite Chapter Cite Chapter

MLA

Walia, Vaibhav, and Munish Garg. "Mitochondrial Dysfunction in Aging and Neurodegeneration." Handbook of Research on Critical Examinations of Neurodegenerative Disorders, edited by Md. Sahab Uddin and Md. Shah Amran, IGI Global, 2019, pp. 76-101. https://doi.org/10.4018/978-1-5225-5282-6.ch004

APA

Walia, V. & Garg, M. (2019). Mitochondrial Dysfunction in Aging and Neurodegeneration. In M. Uddin & M. Amran (Eds.), Handbook of Research on Critical Examinations of Neurodegenerative Disorders (pp. 76-101). IGI Global. https://doi.org/10.4018/978-1-5225-5282-6.ch004

Chicago

Walia, Vaibhav, and Munish Garg. "Mitochondrial Dysfunction in Aging and Neurodegeneration." In Handbook of Research on Critical Examinations of Neurodegenerative Disorders, edited by Md. Sahab Uddin and Md. Shah Amran, 76-101. Hershey, PA: IGI Global, 2019. https://doi.org/10.4018/978-1-5225-5282-6.ch004

Export Reference

Mendeley
Favorite

Abstract

Mitochondria are a dynamic organelle of the cell involved in the various biological processes. Mitochondria are the site of the adenosine triphosphate (ATP) production, electron transport chain (ETC), oxidation of fatty acids, tricarboxylic acid (TCA), and cellular apoptosis. Besides these, mitochondria are the site of production of reactive oxygen species (ROS), which further disrupts the normal functioning of this organelle also making mitochondria itself as an important target of oxidative stress. Thus, mitochondria serve as an important target in the process of neurodegeneration. In the present chapter, the authors describe mitochondria and its functioning, dynamics, and the mitochondrial dysfunction in aging and neurodegenerative disorders (NDs).

Request Access

You do not own this content. Please login to recommend this title to your institution's librarian or purchase it from the IGI Global bookstore.