Welcome to the InfoSci Platform
Preparation and Characterization of Biopolymeric Nanoparticles as Drug Delivery Vehicles: A Comparative Study

Preparation and Characterization of Biopolymeric Nanoparticles as Drug Delivery Vehicles: A Comparative Study

Sai S. Sagiri, Suraj K. Nayak, S. Lakshmi, Kunal Pal
Copyright: © 2018 |Pages: 22
ISBN13: 9781522530237|ISBN10: 1522530231|EISBN13: 9781522530244
DOI: 10.4018/978-1-5225-3023-7.ch010
Cite Chapter Cite Chapter

MLA

Sagiri, Sai S., et al. "Preparation and Characterization of Biopolymeric Nanoparticles as Drug Delivery Vehicles: A Comparative Study." Emergent Research on Polymeric and Composite Materials, edited by R. Somashekar and Thejas Urs G., IGI Global, 2018, pp. 225-246. https://doi.org/10.4018/978-1-5225-3023-7.ch010

APA

Sagiri, S. S., Nayak, S. K., Lakshmi, S., & Pal, K. (2018). Preparation and Characterization of Biopolymeric Nanoparticles as Drug Delivery Vehicles: A Comparative Study. In R. Somashekar & T. Urs G. (Eds.), Emergent Research on Polymeric and Composite Materials (pp. 225-246). IGI Global. https://doi.org/10.4018/978-1-5225-3023-7.ch010

Chicago

Sagiri, Sai S., et al. "Preparation and Characterization of Biopolymeric Nanoparticles as Drug Delivery Vehicles: A Comparative Study." In Emergent Research on Polymeric and Composite Materials, edited by R. Somashekar and Thejas Urs G., 225-246. Hershey, PA: IGI Global, 2018. https://doi.org/10.4018/978-1-5225-3023-7.ch010

Export Reference

Mendeley
Favorite

Abstract

In recent years, the use of biopolymeric nanoparticles as vehicles for drug delivery has increased exponentially. In the present study, chitosan and gelatin nanoparticles were prepared by ionic gelation and desolvation methods, respectively. Salicylic acid was used as the model drug. The nanoparticles were characterized using SEM, XRD analysis and FTIR spectrophotometric studies. In vitro drug release experiments were carried out to understand the mechanism of drug release. SEM micrographs showed the formation of spherical nanoparticles. XRD studies indicated a higher crystalline nature of the chitosan nanoparticles as compared to the gelatin nanoparticles. FTIR studies indicated the presence of salicylic acid within the drug- loaded nanoparticles. Drug release studies indicated that the developed nanoparticles may be used as carriers for various bioactive agents.

Request Access

You do not own this content. Please login to recommend this title to your institution's librarian or purchase it from the IGI Global bookstore.