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Study of Basic Concepts on the Development of Protein Microarray - Gene Expression Profiling: Protein Microarray

Study of Basic Concepts on the Development of Protein Microarray - Gene Expression Profiling: Protein Microarray

P. Sivashanmugam, Arun C., Selvakumar P.
Copyright: © 2016 |Pages: 33
ISBN13: 9781522504276|ISBN10: 1522504273|EISBN13: 9781522504283
DOI: 10.4018/978-1-5225-0427-6.ch013
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MLA

Sivashanmugam, P., et al. "Study of Basic Concepts on the Development of Protein Microarray - Gene Expression Profiling: Protein Microarray." Handbook of Research on Computational Intelligence Applications in Bioinformatics, edited by Sujata Dash and Bidyadhar Subudhi, IGI Global, 2016, pp. 263-295. https://doi.org/10.4018/978-1-5225-0427-6.ch013

APA

Sivashanmugam, P., C., A., & P., S. (2016). Study of Basic Concepts on the Development of Protein Microarray - Gene Expression Profiling: Protein Microarray. In S. Dash & B. Subudhi (Eds.), Handbook of Research on Computational Intelligence Applications in Bioinformatics (pp. 263-295). IGI Global. https://doi.org/10.4018/978-1-5225-0427-6.ch013

Chicago

Sivashanmugam, P., Arun C., and Selvakumar P. "Study of Basic Concepts on the Development of Protein Microarray - Gene Expression Profiling: Protein Microarray." In Handbook of Research on Computational Intelligence Applications in Bioinformatics, edited by Sujata Dash and Bidyadhar Subudhi, 263-295. Hershey, PA: IGI Global, 2016. https://doi.org/10.4018/978-1-5225-0427-6.ch013

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Abstract

The physical and biological activity of any organisms is mainly depended on the genetic information which stored in DNA. A process at which a gene gives rise to a phenotype is called as gene expression. Analysis of gene expression can be used to interpret the changes that occur at biological level of a stressed cell or tissue. Hybridization technology helps to study the gene expression of multiple cell at a same time. Among them microarray technology is a high- throughput technology to study the gene expression at transcription level (DNA) or translation level (Protein). Analysis the protein only can predict the accurate changes that happens in a tissue, when they are infected by a disease causing organisms. Protein microarray mainly used to identify the interactions and activities of proteins with other molecules, and to determine their function for a system at normal state and stressed state. The scope of this chapter is to outline a detail description on the fabrication, types, data analysis, and application of protein microarray technology towards gene expression profiling.

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