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Current Nutrition & Food Science

Editor-in-Chief

ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

Mini-Review Article

Nutraceuticals from Marine Bionetworks

Author(s): Abhitav Tiwari, Shambhawi Pritam, Keerti Mishra, Mehshara Khan, Neeraj Upmanyu and Dipanjana Ghosh *

Volume 15, Issue 4, 2019

Page: [338 - 344] Pages: 7

DOI: 10.2174/1573401314666180109153825

Price: $65

Abstract

“Nutrition” and “Pharmaceutical” together build up the perception of “Nutraceuticals” that refer to the food or dietary supplements that help to incorporate additional health benefits to the fundamental sustenance accomplished on daily basis. Each nutraceutical contains one or more bioactive molecules that are usually obtained by chemical and/ or biotechnological synthesis or by extraction from natural sources. Among the natural sources, marine bionetwork possess immense potential for the presence of bioactive compounds. Some of these bioactive compounds as isolated from marine sources, have potential use as nutraceuticals. This mini review provides a brief overview of nutraceutical compounds from marine sources that are currently under research and/or have been commercialized. A detailed discussion on the biochemical categories of compounds and the marine organisms that play as potential sources of these bioactive nutraceutical compounds have been included.

Keywords: Dietary supplements, marine flora and fauna, nutraceuticals, polysaccharides, proteins, vitamins and minerals.

Graphical Abstract
[1]
Palthur MP, Palthur SS, Chitta SK. Nutraceuticals: Concept and regulatory scenario. Int J Pharma Sci 2010; 2: 14-20.
[2]
Liu RH. Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals. Am J Clin Nutr 2003; 78: 517S-20S.
[3]
Keith WG. Marine products for healthcare: Functional and bioactive nutraceutical compounds from the ocean, Vazhiyil Venugopal. In: Functional Foods and Nutraceuticals Series. CRC Press Taylor and Francis Group Boca Raton, FL, USA 2009; pp. 48-54.
[4]
Montaser R, Luesch H. Marine natural products: A new wave of drugs? Future Med Chem 2011; 3: 1475-89.
[5]
Blunt JW, Copp BR, Keyzers RA, Munro MHG, Prinsep MR. Marine natural products. Nat Prod Rep 2012; 29: 144-222.
[6]
Randy CFC, Tzi BN, Jack HW. Marine peptides: Bioactivities and applications. Mar Drugs 2015; 13: 4006-43.
[7]
Blunt JW, Copp BR, Keyzers RA, Munro MHG, Prinsep MR. Marine natural products. Nat Prod Rep 2014; 31: 160-258.
[8]
Murray BA, FitzGerald RJ. Angiotensin converting enzyme inhibitory peptides derived from food proteins, Biochemistry, bioactivity and production. Curr Pharm Des 2007; 13: 773-91.
[9]
Agyei D, Danquah K. Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides. Biotechnol Adv 2011; 29: 272-7.
[10]
Minkiewicz P, Dziuba J, Michalska J. Bovine meat proteins as potential precursors of biologically active peptides-a computational study based on the BIOPEP database. Food Sci Technol Int 2011; 17: 39-45.
[11]
Balti R, Bougatef A, Sila A, Guillochon D, Dhulster P, Arroume NN. Nine novel angiotensin I-converting enzyme (ACE) inhibitory peptides from cuttlefish (Sepia officinalis) muscle protein hydrolysates and antihypertensive effect of the potent active peptide in spontaneously hypertensive rats. Food Chem 2015; 170: 519-25.
[12]
Cudennec B, Balti R, Ravallec R, et al. In vitro evidence for gut hormone stimulation release and dipeptidyl-peptidase IV inhibitory activity of protein hydrolysate obtained from cuttlefish (Sepia officinalis) viscera. Food Res Int 2015; 78: 238-45.
[13]
Balti R, Bougatef A, Guillochon D, Dhulster P, Nasri M, Arroume NN. Changes in arterial blood pressure after single oral administration of cuttlefish (Sepia officinalis) muscle derived peptides in spontaneously hypertensive rats. J Funct Foods 2012; 4: 611-7.
[14]
Balti R, Arroume NN, Adjé EB, Guillochon D, Nasri M. Analysis of novel angiotensin I-converting enzyme inhibitory peptides from enzymatic hydrolysates of cuttlefish (Sepia officinalis) muscle proteins. J Agric Food Chem 2010; 58: 3840-6.
[15]
Balti R, Arroume NN, Bougatef A, Guillochon D, Nasri M. Three novel angiotensin I-converting enzyme (ACE) inhibitory peptides from cuttlefish (Sepia officinalis) using digestive proteases. Food Res Int 2010; 43: 1136-43.
[16]
Rajapakse NJ, Mendis WK, Moon E, Kim SH. A novel anticoagulant purified from fish protein hydrolysate inhibits factor XIIa and platelet aggregation. Life Sci 2005; 76: 2607-19.
[17]
Fouchereau P, Duvail M, Michel L, Gildberg C, Batista A, Gal IYI. Isolation of an acid fraction from a fish protein hydrolysate with a calcitonin-generelated-peptide-like biological activity. Biotechnol Appl Biochem 1999; 29: 87-92.
[18]
Wijesekara I, Kim SK. Angiotensin-i-converting enzyme (ACE) inhibitors from marine resources: Prospects in the pharmaceutical industry. Mar Drugs 2010; 8: 1080-93.
[19]
MOs L. Jack J, Cullon D, Montour L, Alleyne C, Ross PS. The importance of marine foods to a near-urban first nation community in coastal British Columbia, Canada: Toward a risk-benefit assessment. J Toxicol Environ Health A 2004; 67: 791-808.
[20]
Hu GP, Yuan J, Sun L, et al. Statistical research on marine natural products based on data obtained between 1985 and 2008. Mar Drugs 2011; 9: 514-25.
[21]
Mayer AMS, Rodriguez AD, Berlinck RGS, Hamann MT. Marine pharmacology in 2005-2006: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, anti-tuberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action. Biochim Biophys Acta 2009; 1790: 283-308.
[22]
Balti R, Jridi M, Sila A, et al. Extraction and functional properties of gelatin from the skin of cuttlefish (Sepia officinalis) using smooth hound crude acid protease-aided process. Food Hydrocoll 2011; 25: 943-50.
[23]
Uriz M, Turon X, Becerro MA, Agell G. Siliceous spicules and skeleton frameworks in sponges: Origin, diversity, ultrastructural patterns, and biological functions. Microsc Res Tech 2003; 62: 279-99.
[24]
Thoms C, Schupp PJ. Chemical defence strategies in sponges: A review. In: Custodian MR, Hajdu GL, Hajdu E, Muricy G, Eds.Porifera Research: Biodiversity, Innovation and Sustainability IMOS: Rio de Janeiro. Museu Nacional, Brazil 2007; pp. 627-37.
[25]
Kim SK. Chitin chitosan oligosaccharides and their derivatives: Biological activities and applicationsCRC Taylor & Francis: Boca Raton, FL, USA. 2010; p. 666.
[26]
Smith VJ, Desbois AP, Dyrynda EA. Conventional and unconventional antimicrobials from fish, marine invertebrates and micro-algae. Mar Drugs 2010; 8: 1213-62.
[27]
Tou JC, Jaczynski J, Chen YC. Krill for human consumption, Nutritional value and potential health benefits. Nutr Rev 2007; 65: 63-77.
[28]
Sibilla S, Martin G, Sarah B, Anil BR, Licia G. An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. Open Nutraceuticals J 2015; 8: 29-42.
[29]
Truelstrup HL, Gill TA. Solubility and antimicrobial efficacy of protamine on Listeria monocytogenes and Escherichia coli as influenced by pH. J Appl Microbiol 2000; 88: 1049-55.
[30]
Berteau O, Mulloy B. Sulfatedfucans fresh perspectives Structures, functions, and biological properties of sulphated fucans and an overview of enzymes active toward this class of polysaccharide. Glycobiology 2003; 13: 29R-40R.
[31]
Mansour MB, Balti R, Ollivier V, Jannet HB, Chaubet F, Maaroufi RM. Characterization and anticoagulant activity of a fucosylated chondroitin sulfate with unusually procoagulant effect from sea cucumber. Carbohydr Polym 2017; 174: 760-71.
[32]
Sayari N, Balti R, Mansour MB, et al. Anticoagulant properties and cytotoxic effect against HCT116 human colon cell line of sulfated glycosaminoglycans isolated from the Norway lobster (Nephrops norvegicus) shell. Biomed Pharmacother 2016; 80: 322-30.
[33]
Kim SK, Ravichandran YD, Khan SB, Kim YT. Prospective of the cosmeceuticals derived from marine organisms. Biotechnol Bioprocess Eng 2008; 13: 511-23.
[34]
Vidanarachchi JK, Kurukulasuriya M. . Industrial Applications of Marine Cosmeceuticals, Marine Cosmeceuticals: Latest Trends and Prospects Taylor & Francis: New York 2011
[35]
Kimura A, Kuramoto M. Influence of seaweeds on metabolism of cholesterol and anticoagulant actions of seaweed. Tokushima J Exp Med 1974; 21: 79-88.
[36]
Spagnuolo PA. Kappa carrageenan interactions in system containing casein micelles and polysaccharide stabilizers. Food Hydrocoll 2005; 19: 371.
[37]
Choi BD, Choi YJ. Nutraceutical functionalities of polysaccharides from marine invertebrates. Adv Food Nutr Res 2012; 65: 11-30.
[38]
Parr RM, Aras NK, Iyengar GV. Dietary intakes of essential trace elements. Results from total diet studies supported by the IAEA. J Radioanal Nucl Chem 2006; 270: 155-61.
[39]
Diaz-Lopez M, Garcia-Carreno FL. Applications of fish and shellfish enzymes in food and feed products. In: Haard NF, Simpson BK, Eds.Seafood Enzymes. Marcel Dekker Inc New York 2000; pp. 571-618.
[40]
Hamed I, Özogul F, Özogul Y, Regenstein JM. Marine bioactive compounds and their health benefits: A review Comp Rev food Sci Food Safety 2015; 14: 446-65
[41]
Lordan S, Ross RP, Stanton C. Marine bioactives as functional food ingredients: Potential to reduce the incidence of chronic diseases. Mar Drugs 2011; 9: 1056-100.
[42]
Kim SK, Taylor S. Marine medicinal foods: Implications and applications, macro and microalgae.In: Kim S-K, Ed.Food and Nutrition ResearchAcademic Press: San Diego, CA. 2011; pp. 358-63.
[43]
Ito K, Hori K. Seaweed chemical composition and potential food uses. Food Rev Int 1989; 5: 101-44.
[44]
Rupérez P. Mineral content of edible marine seaweeds. Food Chem 2002; 79: 23-6.
[45]
Shibata T, Ishimaru K, Kawaguchi S, Yoshikawa H, Hama Y. Antioxidant activities of phlorotannins isolated from Japanese Laminariaceae. J Appl Phycol 2008; 20: 705-11.
[46]
Act J, Pytkowska K. Flavonoids as components of biologically active cosmeceuticals. Clin Dermatol 2008; 26: 347-57.
[47]
Volkman JK. Sterols in microorganisms. Appl Microbiol Biotechnol 2003; 60: 495-506.
[48]
Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune krill oil on the clinical course of hyperlipidemia. Altern Med Rev 2004; 9: 420-8.
[49]
Wall R, Ross RP, Fitzgerald GF, Stanton C. Fatty acids from fish: The anti-inflammatory potential of long-chain omega-3 fatty acids. Nutr Rev 2010; 68: 280-9.
[50]
Mac AP, Gill CIR, Brooks M, Campbell R, Rowland IR. Nutritional value of edible seaweeds. Nutr Rev 2007; 12: 535-43.
[51]
Plaza M, Cifuentes A, Ibanez E. In the search of new functional food ingredients from algae. Trends Food Sci Technol 2008; 19: 31-9.
[52]
Gomez OE, Jimenez EA, Ruperez P. Dietary fibre and physico-chemical properties of several edible seaweeds from the North-western Spanish coast. Food Res Int 2010; 9: 2289-94.
[53]
Fleurence J. Seaweed proteins, Biochemical nutritional aspects and potential uses. Trends Food Sci Technol 1999; 10: 25-8.
[54]
Hafiz A, Rasul S, Simone O, Paul M, Glenda G. Marine-based nutraceuticals: An innovative trend in the food and supplement industries. Mar Drugs 2015; 13: 6336-51.
[55]
Khoury D, Anderson GH. Recent advances in dietary proteins and lipid metabolism. Curr Opin Lipidol 2013; 24: 207-13.
[56]
Kim S, Pallela R. Medicinal Foods from Marine Animals: Current Status and Prospects. Adv Food Nutr Res 2012; 65: 1-9.
[57]
Ouellet V, Marois J, Weisnagel SJ, Jacques H. Dietary cod protein improves insulin sensitivity in insulin-resistant men and women, A randomized controlled trial. Diabetes Care 2007; 30: 2816-21.
[58]
Vo TS, Kim SK. Potential anti-HIV agents from marine resources: An overview. Mar Drugs 2010; 8: 2871-92.
[59]
Smith VJ, Desbois AP, Dyrynda EA. Conventional and unconventional antimicrobials from fish, marine, invertebrates and micro-algae. Mar Drugs 2010; 8: 1213-62.
[60]
Tou JC, Jaczynski J, Chen YC. Krill for human consumption. Nutritional value and potential health benefits. Nutr Rev 2007; 65: 63-77.
[61]
Katsura E, Nakamichi R. The iodine intake of Japanese. Eiyo To Shokuryo 1960; 12: 345-7.
[62]
Winwood JR. Recent developments in the commercial production of DHA and EPA rich oils from micro-algae. OCL 2013; 20(6): D604.
[63]
Shaklee PN, Bahr-Davidson J, Prasad S, Johnson K. Process methods for fucoidan purification from seaweed extracts. EP2121767 A1 (2009).
[64]
Ruocco N, Costantini S, Guariniello S, Costantini M. Polysaccharides from the marine environment with pharmacological, cosmeceutical and nutraceutical potential. Molecules 2016; 21: 551.
[65]
Haigh WG. High purity beta-carotene. US5310554 A 1994
[66]
Gates KW. Marine products for healthcare: functional and bioactive nutraceutical compounds from the Ocean, Vazhiyil Venugopal. J Aquat Food Prod Technol 2010; 19(1): 48-54.
[67]
] Global nutraceuticals industry report: 2017-2021 Analysis of the Multi-billion Functional Food and Beverage Industries - Research and Markets. Available from . http://www.prnewswire.com/news-releases/global-nutraceuticals-industry-report-2017-2021.html [accessed on 1 August 2017].
[68]
Nutraceutical Ingredients Market by Type (Pre & Probiotic, Protein, Mineral, Vitamin, Carotenoid, Fiber, and Phytochemical), Application (Food, Dietary Supplement, and Animal Nutrition), Form, Health Benefit, and Region - Global Forecast to 2022. December 2016, Report Code: FB 2211. Available from marketsandmarkets. com [accessed on 10 August 2017].
[69]
Gahche J, Bailey R, Burt V, et al. Dietary Supplement Use Among U.S. Adults Has Increased Since NHANES III (1988-1994). NCHS Data Brief 2011; 61: 1-8.
[70]
Rovira MA, Grau M, Castañer O, Covas MI, Schröder H. Dietary supplement use and health-related behaviors in a Mediterranean population. Nutr Educ Behav 2013; 45: 386-91.
[71]
Foote JA, Murphy SP, Wilkens LR, Hankin JH, Henderson BE, Kolonel LN. Factors associated with dietary supplement use among healthy adults of five ethnicities: The Multiethnic Cohort Study. Am J Epidemiol 2003; 157: 888-97.

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