Abstract
Drug delivery strategies for peptide pharmaceuticals have incorporated a wide range of structure activity relationships, analog generation to impart protease resistance and increased bioavailability, novel formulations, and delivery systems to target optimal therapeutic dosing requirements. Advances in peptide pharmaceuticals have provided products for the treatment of diabetes, obesity, Crohns disease, osteoporosis, cancer, cardiovascular disease, immunotherapy, acromegaly, enuresis, pain, and antimicrobials. Here we review these marketed peptides and new peptidomimetic therapies currently in clinical trials.
Keywords: Peptide, peptidomimetic, drug delivery
Current Pharmaceutical Biotechnology
Title: Advances in Peptide Pharmaceuticals
Volume: 10 Issue: 1
Author(s): Cynthia L. Stevenson
Affiliation:
Keywords: Peptide, peptidomimetic, drug delivery
Abstract: Drug delivery strategies for peptide pharmaceuticals have incorporated a wide range of structure activity relationships, analog generation to impart protease resistance and increased bioavailability, novel formulations, and delivery systems to target optimal therapeutic dosing requirements. Advances in peptide pharmaceuticals have provided products for the treatment of diabetes, obesity, Crohns disease, osteoporosis, cancer, cardiovascular disease, immunotherapy, acromegaly, enuresis, pain, and antimicrobials. Here we review these marketed peptides and new peptidomimetic therapies currently in clinical trials.
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Cite this article as:
Stevenson L. Cynthia, Advances in Peptide Pharmaceuticals, Current Pharmaceutical Biotechnology 2009; 10 (1) . https://dx.doi.org/10.2174/138920109787048634
DOI https://dx.doi.org/10.2174/138920109787048634 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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