Abstract
A series of new potential anticonvulsants have been synthesized. They are N-methyl benzylamides of N-methyl Asp and N-methyl Glu (R and S), benzylamides of some heterocyclic acids and their Noxides and benzylamides of two heteroalicyclic acids. The obtained compounds were evaluated in the Anticonvulsant Screening Project (ASP) of Antiepileptic Drug Development Program (ADDP) of NIH.
Keywords: anticonvulsants, n-methyle-glu, n-methyl-asp derivatives, heterocyclic acid derivaties
Protein & Peptide Letters
Title: Anticonvulsant Activity Of Benzylamides Of Some Amino Acids And Heterocyclic Acids
Volume: 10 Issue: 5
Author(s): Ryszard Paruszewski, Marzanna Strupinska, Grazyna Rostafinska-Suchar and James P. Stables
Affiliation:
Keywords: anticonvulsants, n-methyle-glu, n-methyl-asp derivatives, heterocyclic acid derivaties
Abstract: A series of new potential anticonvulsants have been synthesized. They are N-methyl benzylamides of N-methyl Asp and N-methyl Glu (R and S), benzylamides of some heterocyclic acids and their Noxides and benzylamides of two heteroalicyclic acids. The obtained compounds were evaluated in the Anticonvulsant Screening Project (ASP) of Antiepileptic Drug Development Program (ADDP) of NIH.
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Cite this article as:
Paruszewski Ryszard, Strupinska Marzanna, Rostafinska-Suchar Grazyna and Stables P. James, Anticonvulsant Activity Of Benzylamides Of Some Amino Acids And Heterocyclic Acids, Protein & Peptide Letters 2003; 10 (5) . https://dx.doi.org/10.2174/0929866033478636
DOI https://dx.doi.org/10.2174/0929866033478636 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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