Skip to main content
Log in

Mortality from acute pancreatitis

Late septic deaths can be avoided but some early deaths still occur

  • Published:
International Journal of Pancreatology Aims and scope Submit manuscript

Summary

Methods. A retrospective review was conducted of 105 patients admitted to the Royal Lancaster Infirmary with the diagnosis of acute pancreatitis over a 2-yr period (January 1, 1996 to December 31, 1997).

Results. Six patients admitted during the study period died with a mortality rate of 5.7%. All patients died within 6 d of admission and received care in the intensive care unit. All presented with serious comorbid medical problems and/or developed early multiorgan dysfunction syndrome (MODS). Ten patients underwent pancreatic necrosectomy with no mortality.

Conclusion. In patients with acute pancreatitis, late “septic” deaths resulting from infection of pancreatic tissue can be avoided, but some early deaths are unavoidable owing to serious multiorgan dysfunction often combined with age or other comorbid conditions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Steinberg W, Tenner S. Acute pancreatitis. New Engl J Med 1994; 330: 1198–1210.

    Article  PubMed  CAS  Google Scholar 

  2. Banerjee AK, Kaul A, Beach E, Parberry AC, Doran J, Nicholson ML. An audit of fatal acute pancreatitis. Postgrad Med J 1995; 71: 472–475.

    Article  PubMed  CAS  Google Scholar 

  3. Mann DV, Hershman MJ, Hittinger R., Glazer G. Multicentre audit of death from acute pancreatitis. Br J Surg 1994; 81: 890–893.

    Article  PubMed  CAS  Google Scholar 

  4. de Beaux AC, Palmer KR, Carter DC. Factors influencing morbidity and mortality in acute pancreatitis; an analysis of 279 cases. Gut 1995; 37: 121–126.

    Article  PubMed  Google Scholar 

  5. Blamey SL, Imrie CW, O’Neil J, Gilmour WH, Carter DC. Prognostic factors in acute pancreatitis. Gut 1984; 25: 1340–1346.

    Article  PubMed  CAS  Google Scholar 

  6. Leese T, Shaw D. Comparison of three Glasgow multifactor prognstic scoring systems in acute pancreatitis. Br J Surg 1988; 75: 460–462.

    Article  PubMed  CAS  Google Scholar 

  7. Renner IG, Savage WT III, Pantoja JL, Renner VJ. Death due to acute pancreatitis: a retrospective analysis of 405 autopsy cases. Dig Dis Sci 1985; 30: 1005–1018.

    Article  PubMed  CAS  Google Scholar 

  8. Tran DD, Cuesta MA, Schneider AJ, Wesdorp RI. Prevalence and prediction of multiple organ system failure and mortality in acute pancreatitis. J Crit Care 1993; 8: 145–153.

    Article  PubMed  CAS  Google Scholar 

  9. Bradley EL III, Allen K. A prospective longitudinal study of observation versus surgical intervention in the management of necrotizing pancreatitis. Am J Surg 1991; 161: 19–25.

    Article  PubMed  Google Scholar 

  10. Howard TJ, Wiebke EA, Mogavero G, Kopecky K, et al. Classification and treatment of local septic complications in acute pancreatitis. Am J Surg 1995; 170: 44–50.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lowham, A., Lavelle, J. & Leese, T. Mortality from acute pancreatitis. International Journal of Pancreatology 25, 103–106 (1999). https://doi.org/10.1385/IJGC:25:2:103

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1385/IJGC:25:2:103

Key Words

Navigation