Abstract
Genomics has developed a wide range of tools to identify genes that play roles in specific pathways. However, relating individual genes and alleles to agronomic traits is still quite challenging. We describe how association analysis can be used to relate natural variation at candidate genes with agronomic phenotypes. Association approaches in plants can provide very high resolution and can evaluate a wide range of alleles rapidly. We discuss issues related to experimental design, germplasm sample, molecular assay, population structure, and statistical analysis necessary for association analysis in plants.
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© 2003 Humana Press Inc., Totowa, NJ
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Whitt, S.R., Buckler, E.S. (2003). Using Natural Allelic Diversity to Evaluate Gene Function. In: Grotewold, E. (eds) Plant Functional Genomics. Methods in Molecular Biology™, vol 236. Humana Press. https://doi.org/10.1385/1-59259-413-1:123
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DOI: https://doi.org/10.1385/1-59259-413-1:123
Publisher Name: Humana Press
Print ISBN: 978-1-58829-145-5
Online ISBN: 978-1-59259-413-9
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