Chest
Occupational and Environmental Lung DiseaseMalignant Mesothelioma due to Environmental Exposure to Asbestos: Follow-Up of a Turkish Cohort Living in a Rural Area
Section snippets
Eskisehir Cohort
The Eshisehir cohort was formed as follows: of the 403 villages of Eskisehir, we were able to acquire data, via a questionnaire, from 196 villages. We learned that white soil had been used in 140 villages and was still being used in 126 villages. We randomly chose 67 villages from these 126 villages. We were receiving patients from some of these villages already, and we collected white soil samples from them. We found tremolite or other types of asbestos fiber contamination in a total of 41
Results
The white soil samples from 11 villages all contained asbestos fibers, a high rate of tremolite or tremolite-plus-actinolite-plus-chrysotile mixtures, as well as a lower rate of anthophyllite-plus-chrysotile mixtures. Indoor and outdoor air fiber concentrations were low. Indoor fiber concentrations were from 0.009 to 0.28 fibers per milliliter (f/mL) [mean, 0.089 f/mL]; and outdoor fiber concentrations were 0.009 to 0.04 f/mL (mean, 0.012 f/mL).
Age and sex characteristics of the cohort are on
Discussion
Environmental exposure to asbestos as a cause of mesothelioma has been well documented in many studies.1,3,7,8,9,16,17,18 However, the AMIR values of 114.8/100,000 for men and 159.8/100,000 for women that we established in a cohort of villagers who had been environmentally exposed to asbestos from birth through the use of white soil are the first values presented in the literature for such a cohort. Mesothelioma case series and incidence data from other similar types of exposure19,20 in Turkey
ACKNOWLEDGMENT
The authors thank Tayyibe Kavak, Pinar Atabek, and Kezban Akyuz Simsek from National Institute of Workers Health and Security for their careful fiber analysis, and our teacher, Prof. Dr. Izzettin Baris, for support of our scientific studies.
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This study was partly supported by TÜBİTAK and the Research Fund of Osmangazi University.