ABSTRACT

The recent systematic review [1] and 2014 recommendations [2] from the US Preventive Services Task Force (USPSTF) on vitamin, mineral, and multivitamin supplements have generated important dialog and scientific [3,4] and media debate regarding the role of regular, daily multivitamin use in the prevention of major chronic disease endpoints. The USPSTF concluded that “the current evidence

3.1 Introduction .................................................................................................... 55 3.2 What Are Multivitamin Supplements, and How Are They Used? ................. 56

3.2.1 Definition and Variability of Content ................................................. 56 3.2.2 Prevalence of Multivitamin Supplement Use ..................................... 57 3.2.3 Who Uses Multivitamins? .................................................................. 59

3.3 Multivitamins and Cancer ..............................................................................60 3.3.1 Observational Studies .........................................................................60