ABSTRACT
Fluorescein angiography is the most frequently used imaging technique to document the changes of the BRB function related to DR. It uses sodium fluorescein (NaFl) as an intravenous injected dye and images its presence in the retina and vitreous, requiring dedicated instrumentation operated by well trained personnel. Because of the intravenous dye administration, minimal adverse reactions occur in 5% of the cases as well as other sever complications. Death may still occur in the first 24 to 48 hours for each 220.000 cases (Alfaro, 2006).
