ABSTRACT

Carbon nanomaterial, a superior fluorescent bioimaging agent, possesses low toxicity, stability, and resistance to photobleaching. Hollow fluorescent carbon nanoparticles (HFCNs) are promising as one of the best biocompatible materials compared with traditional dyes and CdTe quantum dots. HFCNs can serve as small containers for applications in catalysis and controlled drug release. HFCNs were added to commercial silica gel to produce fluorescent powder of HFCNs. The nonfluorescent silica powder changes into a fluorescent-response powder just after the adsorption of the HFCNs. The exploration about the prospects of the HFCNs as drug carriers must be preceded by understanding their internal environment. HFCNs are practically nontoxic to biological systems and are promising candidates for applications in biological environments. The vibronic structures of pyrene emission are extremely sensitive to the polarity of the environment, and the peak ratio is routinely used to determine the micropolarity of the medium.