ABSTRACT

The field of molecular medicine covers the medical interventions targeting molecular structures and mechanisms that are involved in disease progression.

In cancer, several molecular mechanisms have been shown to impact its progression, aggressiveness and chemoresistance. Increasing evidence demonstrates the role of nanotechnology and outcome of molecular therapy.

Several books have discussed molecular biology and mechanisms involved in cancer, but this text gives an account of molecular therapeutics in cancer relating to advancements of nanotechnology. It provides a description of the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology.

Key Features:

  • Provides current information in the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology
  • Presents important aspects of nanotechnology in the site-specific delivery of anticancer agents
  • Includes up to date information on oligonucleotide and gene based therapies in cancer
  • Describes small targeted molecules, antibodies and oligonucleotides which have shown to selectively target the molecular structures thereby influencing signal transduction
  • Facilitates discussion between researchers involved in cancer therapy and nanoscientists
  • section Section I|2 pages

    Nanotechnology-Based Approaches to Target Cancer

    chapter 5|24 pages

    Multifunctional Dendrimers as Cancer Nanomedicines

    Peptide-Based Targeting

    section Section III|2 pages

    Oligonucleotides and Gene-Based Therapies

    chapter 13|38 pages

    miRNA Therapeutics to Target Multiple Molecular Pathways

    Current Status, Challenges, and Future Prospects

    chapter 14|30 pages

    Alliance of Lipids with siRNA

    Opportunities and Challenges for RNAi Therapy

    chapter 17|36 pages

    Self-Assembling Programmable RNA Nanoparticles

    From Design and Characterization to Use as an siRNA Delivery Platform