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Feasibility Studies on Avocado as Reducing Agent in TiO2 Doped with Ag2O and Cu2O Nanoparticles for Biological Applications

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The objective of this article is to deal with the application of nanoparticles synthesized using Ag2O and Cu2O were doped with TiO2. The nanoparticles were synthesized using Avocado fruit extract and their applications were evaluated for antimicrobial with cytotoxic properties. The TiO2 doped with Ag2O and Cu2O nanoparticles were characterized using UV-Vis spectrum, Transmission Electron Microscopy (TEM), Fourier Transform Infrared Spectroscopy (FTIR), Elemental X-ray Analysis (EDAX) and X-ray Diffractometer (XRD) patterns respectively. The both Ag2O and Cu2O were doped with TiO2 nanoparticles were in spherical having size ranging from 45–50 nm, and crystalline in nature. Interestingly, the synthesized material exhibited promising activity against the bacterial pathogens such as Escherichia coli, Pseudomonas aeroginosa, Staphylococcus aureus and Salmonella typhi respectively. In addition, the LC50 value (3.929 mg/ml; with 3.102–5.789 as upper and lower limits respectively) against the cell lines were its advantages. Over all, it is concluded that the synthesized material can be used for better biological applications.

Keywords: AG2O DOPED WITH TIO2; ANTIMICROBIAL ACTIVITY; CU2O DOPED WITH TIO2; CYTOTOXIC PROPERTY; SEM; TEM

Document Type: Research Article

Publication date: 01 October 2018

More about this publication?
  • Bionanoscience attempts to harness various functions of biological macromolecules and integrate them with engineering for technological applications. It is based on a bottom-up approach and encompasses structural biology, biomacromolecular engineering, material science, and engineering, extending the horizon of material science. The journal aims at publication of (i) Letters (ii) Reviews (3) Concepts (4) Rapid communications (5) Research papers (6) Book reviews (7) Conference announcements in the interface between chemistry, physics, biology, material science, and technology. The use of biological macromolecules as sensors, biomaterials, information storage devices, biomolecular arrays, molecular machines is significantly increasing. The traditional disciplines of chemistry, physics, and biology are overlapping and coalescing with nanoscale science and technology. Currently research in this area is scattered in different journals and this journal seeks to bring them under a single umbrella to ensure highest quality peer-reviewed research for rapid dissemination in areas that are in the forefront of science and technology which is witnessing phenomenal and accelerated growth.
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