Ravi Karkar
Xiaoyi Zhang
Sean A. Munson
ABSTRACT
The UbiComp community's research in mental health has often focused on depression, but we believe there are many additional opportunities. As participants in this workshop, we will present our initial work to create a portable and self-administered version of the Critical Flicker Frequency (CFF) test. We focus on hepatic encephalopathy, but the test has potential for long-term self-monitoring in a variety of conditions impacting mental health, including cerebro-organic syndromes, multiple sclerosis, Alzheimer's disease, chronic fatigue, and testing of psychoactive drugs. CFF can detect transient effects on the brain and retina which serve as indicators for the above conditions. However, commercial devices for performing the CFF test are expensive and unwieldy. This limits clinical availability of CFF testing, prevents frequent self-administered testing, and reduces access. We explore the possibility of an affordable and portable device for self-administered CFF testing, implemented using commodity components paired with a mobile phone app. Such a device surfaces many future research challenges analogous to those in other areas of mental health. As background for discussions in this workshop, we discuss our initial exploratory design efforts and potential future steps for the project.
- Piero Amodio, Francesca Campagna, Stefania Olianas, Pamela Iannizzi, Daniela Mapelli, Marco Penzo, Paolo Angeli, and Angelo Gatta. (2008). Detection of Minimal Hepatic Encephalopathy: Normalization and Optimization of the Psychometric Hepatic Encephalopathy Score. A Neuropsychological and Quantified EEG Study. Journal of Hepatology, 49(3), 346--353. http://doi.org/10.1016/j.jhep.2008.04.022Google Scholar
Cross Ref
- Jasmohan S. Bajaj. (2010). Review Article: The Modern Management of Hepatic Encephalopathy. Alimentary Pharmacology and Therapeutics, 31(5), 537--547. http://doi.org/10.1111/j.1365-2036.2009.04211.xGoogle ScholarCross Ref
- Peter Ferenci, Alan Lockwood, Kevin Mullen, Ralph Tarter, Karin Weissenborn, and Andres T. Blei. (2002). Hepatic Encephalopathy - Definition, Nomenclature, Diagnosis, and Quantification: Final Report of the Working Party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology, 35(3), 716--721. http://doi.org/10.1053/jhep.2002.31250Google ScholarCross Ref
- Lilian de Greef, Mayank Goel, Min Joon Seo, Eric C Larson, James W. Stout, James A Taylor, and Shwetak N Patel. (2014). Bilicam: Using Mobile Phones to Monitor Newborn Jaundice. Proceedings of the 2014 ACM International Joint Conference on Pervasive and Ubiquitous Computing - UbiComp '14, 331--342. http://doi.org/10.1145/2632048.2632076 Google ScholarDigital Library
- Ieneke J C Hartmann, Michael Groeneweg, Juan C. Quero, Sylvia J. Beijeman, Robert A. de Man, Wim C J Hop, and Solko W. Schalm. (2000). The Prognostic Significance of Subclinical Hepatic Encephalopathy. American Journal of Gastroenterology, 95(8), 2029--2034. http://doi.org/10.1016/S0002-9270(00)01057-1Google ScholarCross Ref
- Gerald Kircheis, Anja Knoche, Norbert Hilger, Frank Manhart, Alfons Schnitzler, Horst Schulze, and Dieter Häussinger. (2009). Hepatic Encephalopathy and Fitness to Drive. Gastroenterology, 137(5), 1706--1715.e9. http://doi.org/10.1053/j.gastro.2009.08.003Google ScholarCross Ref
- Gerald Kircheis, Matthias Wettstein, Lars Timmermann, Alfons Schnitzler, and Dieter Häussinger. (2002). Critical Flicker Frequency for Quantification of Low-Grade Hepatic Encephalopathy. Hepatology, 35(2), 357--366. http://doi.org/10.1053/jhep.2002.30957Google ScholarCross Ref
- Eric C. Larson, Mayank Goel, Gaetano Boriello, Sonya Heltshe, Margaret Rosenfeld, and Shwetak N. Patel. (2012). SpiroSmart: Using a Microphone to Measure Lung Function on a Mobile Phone. Proceedings of the 2012 ACM Conference on Ubiquitous Computing - UbiComp '12, 280--289. http://doi.org/10.1145/2370216.2370261 Google ScholarDigital Library
- Raffaele Nardone, Alexandra C. Taylor, Yvonne Höller, Francesco Brigo, Piergiorgio Lochner, and Eugen Trinka. (2016). Minimal Hepatic Encephalopathy: A Review. Neuroscience Research. http://doi.org/10.1016/j.neures.2016.04.009Google Scholar
- Fred F. Poordad. (2007). Review Article: The Burden of Hepatic Encephalopathy. Alimentary Pharmacology and Therapeutics, 25(SUPPL. 1), 3--9. http://doi.org/10.1111/j.1746-6342.2006.03215.xGoogle Scholar
- Manuel Romero-Gómez, Juan Córdoba, Rodrigo Jover, Juan A. Del Olmo, Marta Ramírez, Ramón Rey, Enrique De Madaria, Carmina Montoliu, David Nuñez, Montse Flavia, Luis Compañy, José M. Rodrigo, and Vicente Felipo. (2007). Value of the Critical Flicker Frequency in Patients with Minimal Hepatic Encephalopathy. Hepatology, 45(4), 879--885. http://doi.org/10.1002/hep.21586Google ScholarCross Ref
- Manuel Romero-Gómez. (2007). Critical Flicker Frequency: It is Time to Break Down Barriers Surrounding Minimal Hepatic Encephalopathy. Journal of Hepatology, 47(1), 10--11. http://doi.org/10.1016/j.jhep.2007.04.005Google ScholarCross Ref
- H Schomerus and W Hamster. (2001). Quality of Life in Cirrhotics with Minimal Hepatic Encephalopathy. Metabolic brain disease, 16(1-2), 37--41. http://doi.org/10.1023/A:1011610427843Google Scholar
- H. Schomerus and W. Hamster. (1998). Neuropsychological Aspects of Portal-Systemic Encephalopathy. Metabolic Brain Disease, 13(4), 361--377. http://doi.org/10.1023/A:1020645110880Google ScholarCross Ref
- F. J. Torlot, M. J W McPhail, and S. D. Taylor-Robinson. (2013). Meta-Analysis: The Diagnostic Accuracy of Critical Flicker Frequency in Minimal Hepatic Encephalopathy. Alimentary Pharmacology and Therapeutics, 37(5), 527--536. http://doi.org/10.1111/apt.12199Google ScholarCross Ref
- Christian Wein, Birthe Popp, Horst Koch, Gerd Oehler, and Peter Schauder. (2004). Minimal Hepatic Encephalopathy Impairs Fitness to Drive. Hepatology, 39(3), 739--745. http://doi.org/10.1002/hep.20095Google ScholarCross Ref
Recommendations
Beacon: Designing a Portable Device for Self-Administering a Measure of Critical Flicker Frequency
Critical flicker frequency (CFF) is the minimum frequency at which a flickering light source appears fused to an observer. Measuring CFF can support early diagnosis of minimal hepatic encephalopathy (MHE), a condition affecting up to 80% of people with ...
Self-tracking for Mental Wellness: Understanding Expert Perspectives and Student Experiences
CHI '17: Proceedings of the 2017 CHI Conference on Human Factors in Computing SystemsPrevious research suggests an important role for self-tracking in promoting mental wellness. Recent studies with college student populations have examined the feasibility of collecting everyday mood, activity, and social data. However, these studies do ...
A 3-Month Randomized Controlled Pilot Trial of a Patient-Centered, Computer-Based Self-Monitoring System for the Care of Type 2 Diabetes Mellitus and Hypertension
This study was performed to evaluate the effects of a patient-centered, tablet computer-based self-monitoring system for chronic disease care. A 3-month randomized controlled pilot trial was conducted to compare the use of a computer-based self-...
Comments