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Biodegradable multi-liposomal containers

  • Medical Polymers
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Abstract

The method of preparing biodegradable multi-liposomal containers via modification of anionic liposomes with a cationic polymer and subsequent adsorption of the obtained liposome-polymer cationic complex on the surfaces of negatively charged polylactide micelles with grafted polyoxyethylene chains is described. Liposomes preserve their integrity in a ternary micelle-polycation-liposome complex, a circumstance that allows the complex to be used as a multi-liposomal container for encapsulation of bioactive compounds.

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Authors and Affiliations

  1. Faculty of Chemistry, Moscow State University, Moscow, 119991, Russia

    A. A. Efimova, A. V. Sybachin & A. A. Yaroslavov

  2. National Research Centre-Kurchatov Institute, pl. Akademika Kurchatova 1, Moscow, 123182, Russia

    S. N. Chvalun, A. I. Kulebyakina & E. V. Kozlova

Authors
  1. A. A. Efimova
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  2. A. V. Sybachin
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  3. S. N. Chvalun
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  4. A. I. Kulebyakina
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  5. E. V. Kozlova
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  6. A. A. Yaroslavov
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Correspondence to A. A. Efimova.

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Efimova, A.A., Sybachin, A.V., Chvalun, S.N. et al. Biodegradable multi-liposomal containers. Polym. Sci. Ser. B 57, 140–144 (2015). https://doi.org/10.1134/S1560090415020050

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  • DOI: https://doi.org/10.1134/S1560090415020050

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