Abstract
5-Phenyl-1H-pyrrole-2,3-diones reacted with malononitrile and 1H-pyrazole-5(4H)-ones to give substituted 6-amino-5-cyano-2′-oxo-5′-phenyl-1′,2′-dihydro-1H-spiro[pyrano[2,3-c]pyrazole-4,3′-pyrroles]. The crystal and molecular structures of ethyl 6-amino-1,1′-dibenzyl-5-cyano-3-methyl-2′-oxo-5′-phenyl-1′,2′-dihydro-1H-spiro[pyrano[2,3-c]pyrazole-4,3′-pyrrole]-4′-carboxylate were determined by X-ray analysis.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Dmitriev, M.V., Silaichev, P.S., Aliev, Z.G., and Maslivets, A.N., Russ. J. Org. Chem., 2011, vol. 47, p. 1165.
Silaichev, P.S., Melyukhin, R.V., Stepanyan, Yu.G., and Maslivets, A.N., Russ. J. Org. Chem., 2012, vol. 48, p. 299.
Dmitriev, M.V., Silaichev, P.S., and Maslivets, A.N., Russ. J. Org. Chem., 2011, vol. 47, p. 1263.
Mishriky, N., Girgis, A.S., Asaad, F.M., Ibrahim, Y.A., Sobieh, U.I., and Fawzy, N.G., Boll. Chim. Farm., 2001, vol. 140, p. 129.
Mandha, S.R., Siliveri, S., Alla, M., Bommena, V.R., Bommineni, M.R., and Balasubramanian, S., Bioorg. Med. Chem. Lett., 2012, vol. 22, p. 5272.
Zaki, M.E.A., Saliman, H.A., Hickal, O.A., and Rashad, A.E., Z. Naturforsch., Teil C, 2006, vol. 61, p. 1.
Ismail, M.M.F., Khalifa, N.M., Fahmy, H.H., Nossier, E.S., and Abdulla, M.M., J. Heterocycl. Chem., 2014, vol. 51, p. 450.
Bhavanarushi, S., Kanakaiah, V., Yakaiah, E., Saddanapu, V., Addlagatta, A., and Rani, J.V., Med. Chem. Res., 2013, vol. 22, p. 2446.
Chobe, S.S., Kamble, R.D., Patil, S.D., Acharya, A.P., Hese, S.V., Yemul, O.S., and Dawane, B.S., Med. Chem. Res., 2013, vol. 22, p. 5197.
Dmitriev, M.V., Silaichev, P.S., Melyukhin, P.V., and Maslivets, A.N., Russ. J. Org. Chem., 2014, vol. 50, p. 1549.
CrysAlisPro, Version 1.171.37.33 (release 27-03-2014 CrysAlis171.NET), Agilent Technologies.
Sheldrick, G.M., Acta Crystallogr., Sect. A, 2008, vol. 64, p. 112.
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © M.V. Dmitriev, P.S. Silaichev, T.V. Sal’nikova, P.V. Melyukhin, A.N. Maslivets, 2015, published in Zhurnal Organicheskoi Khimii, 2015, Vol. 51, No. 6, pp. 900–903.
Rights and permissions
About this article
Cite this article
Dmitriev, M.V., Silaichev, P.S., Sal’nikova, T.V. et al. Three-component spiro heterocyclization of 1H-pyrrole-2,3-diones with malononitrile and pyrazolones. Crystal and molecular structure of a spiro[pyrano[2,3-c]-pyrazole-4,3′-pyrrole]. Russ J Org Chem 51, 884–887 (2015). https://doi.org/10.1134/S1070428015060111
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1070428015060111