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Chiral furan-2-yl-substituted reagents based on (+)-α-methylbenzylamine

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Abstract

The Schiff base obtained by condensation of furfural with (+)-α-methylbenzylamine was reduced with sodium tetrahydridoborate, and the resulting amine was alkylated with methyl iodide to obtain the corresponding chiral tertiary amine. Oxidation of the reduction product with m-chloroperoxybenzoic acid gave (1R)-N-(furan-2-ylmethylidene)-1-phenylethanamine N-oxide.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ufa Research Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, 450054, Bashkortostan, Russia

    Z. R. Valiullina, S. S. Gataullin, B. Ya. Tsirel’son, R. F. Valeev & M. S. Miftakhov

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  1. Z. R. Valiullina
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  2. S. S. Gataullin
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  3. B. Ya. Tsirel’son
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  4. R. F. Valeev
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  5. M. S. Miftakhov
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Correspondence to Z. R. Valiullina.

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Original Russian Text © Z.R. Valiullina, S.S. Gataullin, B.Ya. Tsirel’son, R.F. Valeev, M.S. Miftakhov, 2012, published in Zhurnal Organicheskoi Khimii, 2012, Vol. 48, No. 3, pp. 439–441.

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Valiullina, Z.R., Gataullin, S.S., Tsirel’son, B.Y. et al. Chiral furan-2-yl-substituted reagents based on (+)-α-methylbenzylamine. Russ J Org Chem 48, 439–441 (2012). https://doi.org/10.1134/S1070428012030189

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  • DOI: https://doi.org/10.1134/S1070428012030189

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