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Reaction of 4-hydroxycoumarin with arylglyoxals and ureas

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Abstract

One-pot condensation of 4-hydroxycoumarin with arylglyoxals and ureas gave 4-aryl-5-(4-hydroxy-2-oxo-2H-chromen-3-yl)-1H-imidazol-2(3H)-ones. The same compounds may be obtained from aroylbis(4-hydroxy-2-oxo-2H-chromen-3-yl)methanes and urea. The reaction of 4-bromobenzaldehyde with 4-hydroxycoumarin in the presence of urea led to the formation of the corresponding Michael adduct without participation of urea.

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Authors and Affiliations

  1. Karazin Khar’kov National University, pl. Svobody 4, Khar’kov, 61077, Ukraine

    N. N. Kolos, L. L. Gozalishvili & E. N. Sivokon’

  2. State Scientific Institution “Institute for Single Crystals,”, National Academy of Sciences of Ukraine, 60 Lenin ave., Kharkov, 61001, Ukraine

    I. V. Knyazeva

Authors
  1. N. N. Kolos
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  2. L. L. Gozalishvili
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  3. E. N. Sivokon’
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  4. I. V. Knyazeva
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Correspondence to N. N. Kolos.

Additional information

Original Russian Text © N.N. Kolos, L.L. Gozalishvili, E.N. Sivokon’, I.V. Knyazeva, 2009, published in Zhurnal Organicheskoi Khimii, 2009, Vol. 45, No. 1, pp. 124–129.

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Kolos, N.N., Gozalishvili, L.L., Sivokon’, E.N. et al. Reaction of 4-hydroxycoumarin with arylglyoxals and ureas. Russ J Org Chem 45, 119–125 (2009). https://doi.org/10.1134/S1070428009010151

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  • DOI: https://doi.org/10.1134/S1070428009010151

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