Abstract
Cyclocondensation of 3-amino-5-methylpyrazole with 2-arylmethylidene-5,5-dimethylcyclohexane-1,3-diones or 9-aryl-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-diones, as well as with synthetic precursors of the latter (para-substituted benzaldehydes and dimedone), in dimethylformamide or methanol gives the corresponding 4-aryl-3,7,7-trimethyl-2,4,6,7,8,9-hexahydropyrazolo[3,4-b]quinolin-5-ones. The structure of 4-(4-methoxyphenyl)-3,7,7-trimethyl-2,4,6,7,8,9-hexahydropyrazolo[3,4-b]quinolin-5-one was proved by the X-ray diffraction data.
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Original Russian Text © V.V. Lipson, M.G. Shirobokova, O.V. Shishkin, S.V. Shishkina, 2006, published in Zhurnal Organicheskoi Khimii, 2006, Vol. 42, No. 7, pp. 1034–1039.
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Lipson, V.V., Shirobokova, M.G., Shishkin, O.V. et al. Synthesis of partially hydrogenated pyrazolo[3,4-b]quinolinones by condensation of 3-amino-5-methylpyrazole with aromatic aldehydes and dimedone. Russ J Org Chem 42, 1015–1021 (2006). https://doi.org/10.1134/S1070428006070141
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DOI: https://doi.org/10.1134/S1070428006070141