Abstract
A series of fused pyrimidine-3-carbonitrile derivatives were synthesized starting from 5-amino-1-(8-hydroxy-7-iodoquinoline-5-sulfonyl)-1H-pyrazole-3,4-dicarbonitrile, and their structures were determined using spectroscopic and elemental analysis data.
Similar content being viewed by others
Change history
14 June 2018
The project was financially supported by King Saud University, Vice Deanship of Research Chairs.
References
Nitulescu, G.M., Draghici, C., Olaru, O.T., Matei, L., Ioana, A., Dragu, L.D., and Bleotu, C., Bioorg. Med. Chem., 2015, vol. 23, no. 17, p. 5799. doi 10.1016/j.bmc.2015.07.010
Shi, J.B., Tang, W.J., Qi, X.B., Li, R., and Liu, X.H., Eur. J. Med. Chem., 2015, vol. 90, p. 889. doi 10.1016/j.ejmech.2014.12.013
Reddy, T.S., Kulhari, H., Reddy, V.G., Bansal, V., Kamal, A., and Shukla, R., Eur. J. Med. Chem., 2015, vol. 101, p. 790. doi 10.1016/j.ejmech.2015.07.031
Yewale, S.B., Ganorkar, S.B., Baheti, K.G., and Shelke, R.U., Bioorg. Med. Chem. Lett., 2012, vol. 22, p. 6616. doi 10.1016/j.bmcl.2012.08.119
He, H.Y., Zhao, J.N., Jia, R., Zhao, Y.L., Yang, S.Y., Yu, L.T., and Yang, L., Molecules, 2011, vol. 16, no. 12, p. 10685. doi 10.3390/molecules161210685
Liao, S., Xing, L., and Hamper, B., Tetrahedron Lett., 2013, vol. 54, no. 50, p. 6855. doi 10.1016/j.tetlet.2013.10.021
Khobragade, C.N., Bodade, R.G., Konda, S.G., Dawane, B.S., and Manwar, A.V., Eur. J. Med. Chem., 2010, vol. 45, no. 4, p. 1635. doi 10.1016/j.ejmech.2009.12.040
Rostamizadeh, S., Nojavan,, M., Aryan, R., Sadeghian, H., and Davoodnejad, M., Chin. Chem. Lett., 2013, vol. 24, no. 7, p. 629. doi 10.1016/j.cclet.2013.04.035
Rashad, A.E., Mahmoud, A.E., and Ali, M.M., Eur. J. Med. Chem., 2011, vol. 46, no. 4, p. 1019. doi 10.1016/j.ejmech.2011.01.013
Hassan, G.S., Kadry, H.H., Abou-Seri, S.M., Ali, M.M., and Mahmoud, A.E., Bioorg. Med. Chem., 2011, vol. 19, no. 22, p. 6808. doi 10.1016/j.bmc.2011.09.036
Desai, N.C., Joshi, V.V., Rajpara, K.M., Vaghani, H.V., and Satodiya, H.M., J. Fluorine Chem., 2012, vol. 142, p. 67. doi 10.1016/j.jfluchem.2012.06.021
Nossier, E.S., Fahmy, H.H., Khalifa, N.M., El-Eraky, W.I., and Baset, M.A., Molecules, 2017, vol. 22, p. 512. doi 10.3390/molecules22040512
Ismail, M.F., Khalifa, N.M., Fahmy, H.H., Nossier, E.S., and Abdulla, M.M., J. Heterocycl. Chem., 2014, vol. 51, p. 450. doi 10.1002/jhet.1757
Fahmy, H.H., Khalifa, N.M., Nossier, E.S., Abdalla, M.M., and Ismai, M.M., Acta Pol. Pharm., 2012, vol. 69, no. 3, p. 411. PMID: 22594255.
Author information
Authors and Affiliations
Corresponding author
Additional information
The text was submitted by the authors in English.
Rights and permissions
About this article
Cite this article
Khalifa, N.M., Eweas, A.F. & Amr, A.E. Synthesis and Reactions of Novel Fused 1-(8-Hydroxy-7-iodoquinoline-5-sulfonyl)-1H-pyrazolo-[3,4-d]pyrimidine-3-carbonitrile Derivatives. Russ J Gen Chem 88, 560–563 (2018). https://doi.org/10.1134/S107036321803026X
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S107036321803026X