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Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-2-alkyloxy-6-substituted pyridine-3-carbonitriles

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Abstract

A group of new 2-alkyloxypyridine-3-carbonitriles linked pyrenyl-pyrazole functions has been obtained via reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different methyl aryl ketones. The newly compounds were assured by spectroscopic and elemental analysis.

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Authors and Affiliations

  1. Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia

    N. M. Khalifa & M. A. Al-Omar

  2. Therapeutical Chemistry Department, Pharmaceutical and Drug Industries Division, National Research Centre, Dokki, Cairo, 12622, Egypt

    N. M. Khalifa

  3. Department of Chemistry, Faculty of Science, Menoufia University, Menoufia, Egypt

    M. M. Taha

Authors
  1. N. M. Khalifa
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  2. M. A. Al-Omar
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  3. M. M. Taha
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Corresponding author

Correspondence to N. M. Khalifa.

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The text was submitted by the authors in English.

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Khalifa, N.M., Al-Omar, M.A. & Taha, M.M. Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-2-alkyloxy-6-substituted pyridine-3-carbonitriles. Russ J Gen Chem 87, 2966–2969 (2017). https://doi.org/10.1134/S1070363217120398

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  • DOI: https://doi.org/10.1134/S1070363217120398

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