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Synthesis and characterization of novel chalcones linked 3-[1-(3-chlorophenyl)-3-(pyren-1-yl)]-1H-pyrazole moiety

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Abstract

New series of pyrenyl–pyrazole based chalcones have been synthesized and characterized via the condensation of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different substituted acetophenones in alkaline media. Structures of the newly synthesized compounds were elucidated from spectroscopic and elemental analysis data.

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Authors and Affiliations

  1. Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia

    N. M. Khalifa, M. A. Al-Omar & O. M. Ali

  2. Therapeutical Chemistry Department, Pharmaceutical, and Drug Industries Division, National Research Centre, Dokki, Cairo, 12622, Egypt

    N. M. Khalifa

  3. Department of Chemistry, Faculty of Medical and Applied Science, Taif University, Taif, Saudi Arabia

    O. M. Ali

Authors
  1. N. M. Khalifa
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  2. M. A. Al-Omar
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  3. O. M. Ali
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Correspondence to N. M. Khalifa.

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The text was submitted by the authors in English.

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Khalifa, N.M., Al-Omar, M.A. & Ali, O.M. Synthesis and characterization of novel chalcones linked 3-[1-(3-chlorophenyl)-3-(pyren-1-yl)]-1H-pyrazole moiety. Russ J Gen Chem 87, 2699–2702 (2017). https://doi.org/10.1134/S1070363217110275

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  • DOI: https://doi.org/10.1134/S1070363217110275

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